1. |
Akita H, Fujiwara T, Santiwarangkool S, Hossen N, Kajimoto K, El-Sayed A, Tabata Y, Harashima H. "Transcytosis-Targeting Peptide: A Conductor of Liposomal Nanoparticles through the Endothelial Cell Barrier." Small (2015) 12(9): 1212-1221 |
2. |
Kajimoto K§, *, Minami Y§, Harashima H. “Cytoprotective role of the fatty acid binding protein 4 against oxidative and endplasmic reticulum stress in 3T3-L1 adipocytes.” FEBS Open Bio. (2014) 4:602-610. §Equal contribution |
3. |
Tamaru M, Akita H, Nakatani T, Kajimoto K, Sato Y, Hatakeyama H, Harashima H. “Application of apolipoprotein E modified nanoparticles as a carrier for delivering DNA and nucleic acid to the brain.” Int J Nanomed. (2014) 9: 4267-4276. |
4. |
Hossen MN§, Kajimoto K§, Tastumi R§, Hyodo M, Harashima H. “Comparative assessments of crucial factors for a functional ligand-targeted nanocarriers.” J Drug Target. (2014) 22(7): 600-609. §Equal contribution |
5. |
Ikeda Y, Tsuchiya H, Hama S, Kajimoto K, Kogure K. “Resistin regulates the expression of plasminogen activator inhibitor-1 in 3T3-L1 adipocytes.” Biochem Biophys Res Commun. (2014) 448(2) 129-133. |
6. |
Tamaru M, Akita H, Kajimoto K, Sato Y, Hatakeyama H, Karashima H. “An apolipoprotein E modified nanoparticle: Ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells.” Int J Pharm. (2014) 465(1-2): 77-82. |
7. |
Hayashi Y§, Suemitsu E§, Kajimoto K§, Sato Y, Akhter A, Sakurai Y, Hatakeyama H, Hyodo M, Kaji N, Baba Y, Harashima H. “Hepatic monoacylglycerol o-acyltransferase 1 as a promising therapeutic target for steatosis, obesity and type2 diabetes.” Mol Ther Nucleic Acids. (2014) 3, e154. §Equal contribution |
8. |
Hama S, Kimura Y, Mikami A, Shiota K, Toyoda M, Tamura A, Nagasaki Y, Kanamura K, Kajimoto K, Kogure K. “Electric Stimulus Opens Intercellular Spaces in Skin.” J Biol Chem. (2014) 289(4): 2450-2456. |
9. |
Kusumoto K, Akita H, Ishitsuka T, Matsumoto Y, Nomoto T, Furukawa R, El-Sayed A, Hatakeyama H, Kajimoto K, Yamada Y, Kataoka K, Harashima H. “Lipid Envelope-Type Nanoparticle Incorporating a Multifunctional Peptide for Systemic siRNA Delivery to the Pulmonary Endothelium.” ACS Nano. (2013) 7(9): 7534-7541. |
10. |
Ikeda Y, Tsuchiya H, Hama S, Kajimoto K, Kogure K. “Resistin affects lipid metabolism during adipocyte maturation of 3T3-L1 cells.” FEBS J. (2013) 280(22): 5884-5895. |
11. |
Hossen MN, Kajimoto K, Akita H, Hyodo M, Harashima H. “A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication.” J Control Release. (2013) 171(2): 104-112. |
12. |
Hossen MN, Kajimoto K, Akita H, Hyodo M, Ishitsuka T, Harashima H. “Therapeutic assessment of cytochrome C for the prevention of obesity through endothelial cell-targeted nanoparticulate system.” Mol Ther. (2013) 21(3): 533-541. |
13. |
Kajimoto K*, Takayanagi S, Sasaki S, Akita H, Harashima H. “RNA interference-based silencing reveals the regulatory role of fatty acid-binding protein 4 in the production of IL-6 and vascular endothelial growth factor in 3T3-L1 adipocytes.” Endocrinology. (2012) 153(11): 5629-5636. |
14. |
Hossen MN, Kajimoto K, Akita H, Hyodo M, Harashima H. “Vascular-targeted nanotherapy for obesity: unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery.” J Control Release. (2012) 163(2): 101-110. |
15. |
Kigasawa K, Miyashita M, Kajimoto K, Kanamura K, Harashima H, Kogure K. “Efficient intradermal delivery of superoxide dismutase using a combination of liposomes and iontophoresis for protection against UV-induced skin damage.” Biol Pharm Bull. (2012) 35(5): 781-785. |
16. |
Hayashi Y, Yamauchi J, Khalil IA, Kajimoto K, Akita H, Harashima H. “Cell penetrating peptide-mediated systemic siRNA delivery to the liver.” Int J Pharm. (2011) 419(1-2): 308-313. |
17. |
Ikeda Y, Hama S, Kajimoto K, Okuno T, Tsuchiya H, Kogure K. “Quantitative comparison of adipocytokine gene expression during adipocyte maturation in non-obese and obese rats.” Biol Pharm Bull. (2011) 34(6): 865-870. |
18. |
Yatsushiro S, Akamine R, Yamamura S, Hino M, Kajimoto K, Abe K, Abe H, Kido J, Tanaka M, Shinohara Y, Baba Y, Ooie T, Kataoka M. “Quantitative analysis of serum procollagen type I C-terminal propeptide by immunoassay on microchip.” PLoS One. (2011) 6(4): e18807. |
19. |
Yamaguchi Y, Yatsushiro S, Yamamura S, Abe H, Abe K, Watanabe M, Kajimoto K, Shinohara Y, Baba Y, Kataoka M. “Ribonuclease protection assay on microchip electrophoresis.” Analyst. (2011) 136(11): 2247-2251. |
20. |
Hatakeyama H, Ito E, Yamamoto M, Akita H, Hayashi Y, Kajimoto K, Kaji N, Baba Y, Harashima H. “A DNA microarray-based analysis of the host response to a nonviral gene carrier: a strategy for improving the immune response.” Mol Ther. (2011) 19(8): 1487-1498. |
21. |
Kigasawa K, Kajimoto K, Nakamura T, Hama S, Kanamura K, Harashima H, Kogure K. “Noninvasive and efficient transdermal delivery of CpG-oligodeoxynucleotide for cancer immunotherapy.” J Control Release. (2011) 150(3): 256-265. |
22. |
Kajimoto K, Yamamoto M, Watanabe M, Kigasawa K, Kanamura K, Harashima H, Kogure K. “Noninvasive and persistent transfollicular drug delivery system using a combination of liposomes and iontophoresis.” Int J Pharm. (2011) 403(1-2): 57-65. |
23. |
Hossen MN, Kajimoto K, Akita H, Hyodo M, Ishitsuka T, Harashima H. “Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue.” J Control Release. (2010) 147(2): 261-268. |
24. |
Hayashi Y, Kajimoto K, Iida S, Sato Y, Mizufune S, Kaji N, Kamiya H, Baba Y, Harashima H. “DNA microarray analysis of whole blood cells and insulin-sensitive tissues reveals the usefulness of blood RNA profiling as a source of markers for predicting type 2 diabetes.” Biol Pharm Bull. (2010) 33(6): 1033-1042. |
25. |
Yamauchi J, Hayashi Y, Kajimoto K, Akita H, Harashima H. “Comparison between a multifunctional envelope-type nano device and lipoplex for delivery to the liver.” Biol Pharm Bull. (2010) 33(5): 926-929. |
26. |
Kajimoto K*, Hossen MN, Hida K, Ohga N, Akita H, Hyodo M, Hida Y, Harashima H. “Isolation and culture of microvascular endothelial cells from murine inguinal and epididymal adipose tissues.” J Immunol Methods. (2010) 357(1-2): 43-50. |
27. |
Tamaru M, Akita H, Fujiwara T, Kajimoto K, Harashima H. “Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis.” Biochem Biophys Res Commun. (2010) 394(3): 587-592. |
28. |
Kigasawa K, Kajimoto K, Hama S, Saito A, Kanamura K, Kogure K. “Noninvasive delivery of siRNA into the epidermis by iontophoresis using an atopic dermatitis-like model rat.” Int J Pharm. (2010) 383(1-2): 157-160. |
29. |
Kigasawa K, Kajimoto K, Watanabe M, Kanamura K, Saito A, Kogure K. “In vivo transdermal delivery of diclofenac by ion-exchange iontophoresis with geraniol.” Biol Pharm Bull. (2009) 32(4): 684-687. |
30. |
Maeda E, Kataoka M, Yatsushiro S, Kajimoto K, Hino M, Kaji N, Tokeshi M, Bando M, Kido J, Ishikawa M, Shinohara Y, Baba Y. “Accurate quantitation of salivary and pancreatic amylase activities in human plasma by microchip electrophoretic separation of the substrates and hydrolysates coupled with immunoinhibition.” Electrophoresis. (2008) 29(9): 1902-1909. |
31. |
Watanabe M, Yamamoto T, Kakuhata R, Okada N, Kajimoto K, Yamazaki N, Kataoka M, Baba Y, Tamaki T, Shinohara Y. “Synchronized changes in transcript levels of genes activating cold exposure-induced thermogenesis in brown adipose tissue of experimental animals.” Biochim Biophys Acta. (2008) 1777(1): 104-112. |
32. |
Hino M, Kataoka M, Kajimoto K, Yamamoto T, Kido J, Shinohara Y, Baba Y. “Efficiency of cell-free protein synthesis based on a crude cell extract from Escherichia coli, wheat germ, and rabbit reticulocytes.” J Biotechnol. (2008) 133(2): 183-189. |
33. |
Maeda E, Kataoka M, Hino M, Kajimoto K, Kaji N, Tokeshi M, Kido J, Shinohara Y, Baba Y. “Determination of human blood glucose levels using microchip electrophoresis.” Electrophoresis. (2007) 28(16): 2927-2933. |
34. |
Kajimoto K, Hiura Y, Sumiya T, Yasui N, Okuda T, Iwai N. “Exclusion of the catechol-o-methyltransferase gene from genes contributing to salt-sensitive hypertension in dahl salt-sensitive rats.” Hypertens Res. (2007) 30(5): 459-467. |
35. |
Ewis AA, El-Samman E, Ali N, Kajimoto K, Shinohara Y, Ishikawa M, Kanayama HO, Baba Y. “Gene expression profile in squamous cell carcinoma of the urinary bladder using complementary deoxyribonucleic acid microarray.” Urol Oncol. (2007) 25(2): 120-127. |
36. |
Yasui N, Kajimoto K, Sumiya T, Okuda T, Iwai N. “The monocyte chemotactic protein-1 gene may contribute to hypertension in Dahl salt-sensitive rats.” Hypertens Res. (2007) 30(2): 185-193. |
37. |
Iwai N, Kajimoto K, Tomoike H, Takashima N. “Polymorphism of CYP11B2 determines salt sensitivity in Japanese.” Hypertension. (2007) 49(4): 825-831. |
38. |
Iwai N, Kajimoto K, Kokubo Y, Tomoike H. “Extensive genetic analysis of 10 candidate genes for hypertension in Japanese.” Hypertension. (2006) 48(5): 901-907. |
39. |
Kajimoto K§, Naraba H§, Iwai N. “MicroRNA and 3T3-L1 pre-adipocyte differentiation.” RNA. (2006) 12(9): 1626-1632. §Equal contribution |
40. |
Iwai N, Kajimoto K, Kokubo Y, Okayama A, Miyazaki S, Nonogi H, Goto Y, Tomoike H. “Assessment of genetic effects of polymorphisms in the MCP-1 gene on serum MCP-1 levels and myocardial infarction in Japanese.” Circ J. (2006) 70(7): 805-809. |
41. |
Elsamman E, Fukumori T, Ewis AA, Ali N, Kajimoto K, Shinohara Y, Ishikawa M, Takahashi M, Nishitani MA, Baba Y, Kanayama HO. “Differences in gene expression between noninvasive and invasive transitional cell carcinoma of the human bladder using complementary deoxyribonucleic acid microarray: preliminary results.” Urol Oncol. (2006) 24(2): 109-115. |
42. |
Kajimoto K, Shioji K, Tago N, Tomoike H, Nonogi H, Goto Y, Iwai N. “Assessment of MEF2A mutations in myocardial infarction in Japanese patients.” Circ J. (2005) 69(10): 1192-1195. |
43. |
Kajimoto K, Shioji K, Ishida C, Iwanaga Y, Kokubo Y, Tomoike H, Miyazaki S, Nonogi H, Goto Y, Iwai N. “Validation of the association between the gene encoding 5-lipoxygenase-activating protein and myocardial infarction in a Japanese population.” Circ J. (2005) 69(9): 1029-1034. |
44. |
Kajimoto K, Terada H, Baba Y, Shinohara Y. “Essential role of citrate export from mitochondria at early differentiation stage of 3T3-L1 cells for their effective differentiation into fat cells, as revealed by studies using specific inhibitors of mitochondrial di- and tricarboxylate carriers.” Mol Genet Metab. (2005) 85(1): 46-53. |
45. |
Unami A, Shinohara Y, Kajimoto K, Baba Y. “Comparison of gene expression profiles between white and brown adipose tissues of rat by microarray analysis.” Biochem Pharmacol. (2004) 67(3): 555-564. |
46. |
Kataoka M, Inoue S, Kajimoto K, Sinohara Y, Baba Y. “Usefulness of microchip electrophoresis for reliable analyses of nonstandard DNA samples and subsequent on-chip enzymatic digestion.” Eur J Biochem. (2004) 271(11): 2241-2247. |
47. |
Kajimoto K, Daikoku T, Kita F, Yamazaki N, Kataoka M, Baba Y, Terada H, Shinohara Y. “PCR-select subtraction for characterization of messages differentially expressed in brown compared with white adipose tissue.” Mol Genet Metab. (2003) 80(1-2): 255-261. |
48. |
Kajimoto K, Daikoku T, Yamazaki N, Terada H, Shinohara Y. “Expression profiles of three isoforms of inositol 1,4,5-trisphosphate receptor in brown adipose tissue of the rat.” Biochem Pharmacol. (2003) 65(6): 995-998. |
49. |
Hino M, Shinohara Y, Kajimoto K, Terada H, Baba Y. “Requirement of continuous transcription for the synthesis of sufficient amounts of protein by a cell-free rapid translation system.” Protein Expr Purif. (2002) 24(2): 255-259. |
50. |
Shinohara Y, Daikoku T, Kajimoto K, Shima A, Yamazaki N, Terada H. “Expression of NAD(+)-dependent isocitrate dehydrogenase in brown adipose tissue.” Biochem Biophys Res Commun. (2001) 281(3): 634-638. |
51. |
Yamazaki N, Shinohara Y, Kajimoto K, Shindo M, Terada H. “Novel expression of equivocal messages containing both regions of choline/ethanolamine kinase and muscle type carnitine palmitoyltransferase I.” J Biol Chem. (2000) 275(41): 31739-31746. |