北海道大学 大学院薬学研究院 創薬化学部門 創薬化学分野 大学院生命科学院 生命分子科学講座

発表論文

2019

"Cobalt-catalyzed Synthesis of Homoallylic Amines from Imines and Terminal Alkenes"

Tanaka, R.; Kojima, M.; Yoshino, T.; Matsunaga, S.
Chem. Lett. 2019, Advance Publication. DOI: 10.1246/cl.190378

"Cp*CoIII-Catalyzed C–H Functionalization and Asymmetric Reactions Using External Chiral Sources"

Yoshino, T.; Matsunaga, S.
Synlett 2019, eFirst. DOI: 10.1055/s-0037-1611814

"C–H γ,γ,γ-Trifluoroalkylation of Quinolines via Visible-Light-Induced Sequential Radical Additions"

Kumagai, Y.; Murakami, N.; Kamiyama, F.; Tanaka, R.; Yoshino, T.; Kojima, M.; Matsunaga, S.
Org. Lett. 2019, 21, 3600. DOI: 10.1021/acs.orglett.9b01015

"Synthesis of Heteroaryl Iodanes(III) via ipso‐Substitution Reactions Using Iodine Triacetate Assisted by HFIP"

Matsuoka, K.; Komami, N.; Kojima, M.; Yoshino, T.; Matsunaga, S.
Asian J. Org. Chem. 2019, Early View. DOI: 10.1002/ajoc.201900200

"Cobalt‐Catalyzed Allylic Alkylation Enabled by Organophotoredox Catalysis"

Takizawa, K.; Sekino, T.; Sato, S.; Yoshino, T.; Kojima, M.; Matsunaga, S.
Angew. Chem., Int. Ed. 2019, Early View. DOI: 10.1002/anie.201902509

"Synthesis of Functionalized Monoaryl‐λ3‐iodanes through Chemo‐ and Site‐selective ipso‐Substitution Reactions"

Komami, N.; Matsuoka, K.; Nakano, A.; Kojima, M.; Yoshino, T.; Matsunaga, S.
Chem. Eur. J. 2019, 25, 1217. DOI: 10.1002/chem.201805970

"Enantioselective C(sp3)–H Amidation of Thioamides Catalyzed by a CobaltIII/Chiral Carboxylic Acid Hybrid System"

Fukagawa, S.; Kato, Y.; Tanaka, R.; Kojima, M.; Yoshino, T.; Matsunaga, S.
Angew. Chem., Int. Ed. 2019, 58, 1153. DOI: 10.1002/anie.201812215
Highlighted in Synfacts.

"One-Step Synthesis of 4H-3,1-Benzoxazin-4-ones from Weinreb Amides and 1,4,2-Dioxazol-5-ones via Cobalt-Catalyzed C-H Bond Activation"

Tanimoto, I.; Kawai, K.; Sato, A.; Yoshino, T.; Matsunaga, S.
HeteroCycles 2019, 99, 118. DOI: 10.3987/COM-18-S(F)48

2018

"Chiral Carboxylic Acid‐Enabled Achiral Rhodium(III)-Catalyzed Enantioselective C−H Functionalization"

Lin, L.; Fukagawa, S.; Sekine, D.; Tomita, E.; Yoshino, T.; Matsunaga, S.
Angew. Chem., Int. Ed. 2018, 57, 12048. DOI: 10.1002/anie.201807610
Highlighted in Synfacts.

"Pentamethylcyclopentadienyl Rhodium(III)-Chiral Disulfonate Hybrid Catalysis for Enantioselective C-H Bond Functionalization"

Satake, S.; Kurihara, T.; Nishikawa, K.; Mochizuki, T.; Hatano, M.; Ishihara, K.; Yoshino, T.; Matsunaga, S.
Nature Catalysis 2018, 1, 585. DOI: 10.1038/s41929-018-0106-5
Author Correction

"5-((3-Bromoallyl)Sulfonyl)-1H-Tetrazoles for Bromodiene Synthesis"

Suzuki, T.; Fukagawa, S.; Yoshino, T.; Anada, M.; Matsunaga, S.
HeteroCycles 2018, 97, 1304. DOI: 10.3987/COM-18-S(T)90

"Weinreb Amide Directed Versatile C-H Bond Functionalization under (η5-Pentamethylcyclopentadienyl)cobalt(III) Catalysis"

Kawai, K.; Bunno, Y.; Yoshino, T.; Matsunaga, S.
Chem. Eur. J. 2018, 24, 10231. DOI: 10.1002/chem.201801750

"Cobalt-catalyzed C(sp3)-H Bond Functionalization Reactions"

Yoshino, T.; Matsunaga, S.
Asian J. Org. Chem. 2018, 7, 1193. DOI: 10.1002/ajoc.201800195

"Synthesis of 1,1'-Spirobiindane-7,7'-Disulfonic Acid and Disulfonimide: Application for Catalytic Asymmetric Aminalization"

Kurihara, T.; Satake, S.; Hatano, M.; Ishihara K.; Yoshino T.; Matsunaga, S.
Chem. Asian. J. 2018, 13, 2378. DOI: 10.1002/asia.201800341

"DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation"

Tomino, T.; Tajiri, H.; Tatsuguchi, T.; Shirai, T.; Oisaki, K.; Matsunaga, S.; Sanematsu, F.; Sakata, D.; Yoshizumi, T.; Maehara, Y.; Kanai, M.; Cote, J.-F.; Fukui, Y.; Uruno Y.
Biochem. Biophys. Res. Commun. 2018, 497, 298. DOI: 10.1016/j.bbrc.2018.02.073

"Synthesis of Fluorine-Containing 6-Arylpurine Derivatives via Cp*Co(III)-Catalyzed C–H Bond Activation"

Murakami, N.; Yoshida, M.; Yoshino, T.; Matsunaga S.
Chem. Pharm. Bull. 2018, 66, 51. DOI: 10.1248/cpb.c17-00797

2017

"Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILRα immune cell receptor"

Furukawa, A.; Kakita, K.; Yamada, T.; Ishizuka, M.; Sakamoto, J.; Hatori, N.; Maeda, N.; Ohsaka, F.; Saitoh, T.; Nomura, T.; Kuroki, K.; Nambu, H.; Arase, H.; Matsunaga, S.; Anada, M.; Ose, T.; Hashimoto, S.; Maenaka, K.
J. Biol. Chem. 2017, 292, 21128. DOI: 10.1074/jbc.M117.799239

"Total Synthesis of Brasilicardins A and C"

Anada M.; Hanari T.; Kakita K.; Kurosaki Y.; Katsuse K.; Sunadoi Y.; Jinushi Y.; Takeda K.; Matsunaga S.; Hashimoto S.
Org. Lett. 2017, 19, 5581. DOI: 10.1021/acs.orglett.7b02728

"2-Hydroxyindoline-3-triethylammonium Bromide: A Reagent for Formal C3-Electrophilic Reactions of Indoles"

Abe T.; Suzuki, T.; Anada M.; Matsunaga, S.; Yamada K.
Org. Lett. 2017, 19, 4275. DOI: 10.1021/acs.orglett.7b01940

"High-Valent Cobalt-Catalyzed C-H Bond Functionalization"

Yoshino T.; Matsunaga S.
Advances in Organometallic Chemistry 2017, 68, 197. DOI: 10.1016/bs.adomc.2017.07.002

"Cp*CoIII-Catalyzed C–H Alkenylation/Annulation Reactions of Indoles with Alkynes: A DFT Study"

Sakata, K.; Eda M.; Kitaoka Y.; Yoshino T.; Matsunaga S.
J. Org. Chem. 2017, 82, 7379. DOI: 10.1021/acs.joc.7b01047

"Catalytic Enantioselective Desymmetrization of meso-Aziridines with Fluoromalonates"

Fukagawa, S.; Xu, Y.; Anada, M.; Yoshino, T.; Matsunaga, S.
HeteroCycles 2017, 94 1337. DOI: 10.3987/COM-17-13725.

"Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1"

Tajiri, H.; Uruno, T.; Shirai, T.; Takaya, S.; Matsunaga, S.; Setoyama, D.; Watanabe, M.; Kukimoto-Niino, M.; Oisaki, K.; Ushijima, M.; Sanematsu, F.; Honma, T.; Terada,T.; Oki,E.; Shirasawa, S.; Maehara, Y.; Kang, D.; Côté, J.-F.; Yokoyama, S.; Kanai, M.; Fukui, Y.
Cell Reports 2017, 19, 969. DOI: 10.1016/j.celrep.2017.04.016

"Stereoselective Synthesis of Tetrasubstituted Alkenes via a Cp*CoIII-Catalyzed C−H Alkenylation/Directing Group Migration Sequence"

Ikemoto. H.; Tanaka, R.; Sakata, K.; Kanai, M.; Yoshino, T.; Matsunaga, S.
Angew. Chem., Int. Ed. 2017, 56 7156. DOI: 10.1002/anie.201703193

"Cp*CoIII-catalyzed directed C–H trifluoromethylthiolation of 2-phenylpyridines and 6-arylpurines"

Yoshida, M.; Kawai, K.; Tanaka, R.; Yoshino, T.; Matsunaga, S.
Chem. Commun. 2017, 53 5974. DOI: 10.1039/C7CC03072J

"A Novel Spiro-heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in Staphylococcus aureus"

Paudel, A.; Hamamoto, H.; Panthee, S.; Kaneko, K.; Matsunaga, S.; Kanai, M.; Suzuki, Y.; Sekimizu, K.
Front. Microbiol. 2017, published online. DOI: 10.3389/fmicb.2017.00712

"Hybrid Catalysis Enabling Room-Temperature Hydrogen Gas Release from N-Heterocycles and Tetrahydronaphthalenes"

Kato, S.; Saga, Y.; Kojima, M.; Fuse,H.; Matsunaga, S.; Fukatsu, A.; Kondo, M.; Masaoka, S.; Kanai, M.
J. Am. Chem. Soc. 2017, 139, 2204. DOI: 10.1021/jacs.7b00253

"(Pentamethylcyclopentadienyl)cobalt(III)-Catalyzed C–H Bond Functionalization: From Discovery to Unique Reactivity and Selectivity"

Yoshino, T.; Matsunaga, S.
Adv. Synth. Catal. 2017, 359, 1245. DOI: 10.1002/adsc.201700042
Selected for a cover picture, DOI: 10.1002/adsc.201700284

"Diastereo- and Enantioselective Construction of 6,7-Dioxabicyclo[2.2.1]heptane Derivatives by a Dirhodium(II)-Catalyzed Intramolecular C-H Insertion Reaction"

Miyazawa, T.; Imai, K.; Ito, M.; Takeda, K.; Anada, M.; Matsunaga, S.; Hashimoto, S.
HeteroCycles 2017, 95, 1211. DOI: 10.3987/COM-16-S(S)72

2016

"Rapid Screening by Cell-Based Fusion Assay for Identifying Novel Antivirals of Glycoprotein B-Mediated Herpes Simplex Virus Type 1 Infection"

Maeda, N.; Furukawa, A; Kakita, K.; Anada, M.; Hashimoto, S.; Matsunaga, S.; Kuroki, K.; Ose, T.; Kato, A.; Arii, J.; Kawaguchi, Y.; Arase, H.; Maenaka, K.
Biol. Pharm. Bull. 2016, 39, 1897. DOI: 10.1248/bpb.b16-00533

"Site- and Regioselective Monoalkenylation of Pyrroles with Alkynes via Cp*CoIII Catalysis"

Tanaka, R.; Ikemoto, H.; Kanai, M.; Yoshino, T.; Matsunaga, S.
Org. Lett. 2016, 18, 5732. DOI: 10.1021/acs.orglett.6b02997

"Enantio-and diastereoselective desymmetrization of α-alkyl-α-diazoesters by dirhodium(II)-catalyzed intramolecular C-H insertion"

Miyazawa, T.; Minami, K.; Ito, M;, Anada, M.; Matsunaga, S.; Hashimoto, S.
Tetrahedron 2016, 72, 3939. DOI: 10.1016/j.tet.2016.05.015

"Cp*CoIII-Catalyzed Dehydrative C–H Allylation of 6-Arylpurines and Aromatic Amides Using Allyl Alcohols in Fluorinated Alcohols"

Bunno, Y.; Murakami, N.; Suzuki, Y.; Kanai, M.; Yoshino, T.; Matsunaga, S.
Org. Lett. 2016, 18, 2216. DOI: 10.1021/acs.orglett.6b00846

"Carbon Dioxide Utilization via Carbonate-promoted C–H Carboxylation"

Banerjee, A; Dick, G. R.; Yoshino, T.; Kanan, M. W.
Nature 2016, 531, 215. DOI: 10.1038/nature17185

2015

"Catalytic Asymmetric Iterative/Domino Aldehyde Cross-Aldol Reactions for the Rapid and Flexible Synthesis of 1,3-Polyols"

Lin. L.; Yamamoto, K.; Mitsunuma, H.; Kanzaki, Y.; Matsunaga, S.; Kanai, M.
J. Am. Chem. Soc. 2015, 137, 15418. DOI: 10.1021/jacs.5b11192

"Cp*CoIII Catalyzed Site-Selective C-H Activation of Unsymmetrical O-Acyl Oximes: Synthesis of Multisubstituted Isoquinolines from Terminal and Internal Alkynes"

Sun, B.; Yoshino, T.; Kanai, M.; Matsunaga, S.
Angew. Chem., Int. Ed. 2015, 54, 12968. DOI: 10.1002/anie.201507744

"Dehydrative Direct C-H Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis"

Suzuki, Y.; Sun, B.; Sakata, K.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Angew. Chem., Int. Ed. 2015, 54, 9944. DOI: 10.1002/anie.201503704

"Cp*Co(III)-catalyzed Oxidative C-H Alkenylation of Benzamides with Ethyl Acrylate"

Suzuki, Y.; Sun, B.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Tetrahedron 2015, 71,4552. DOI: 10.1016/j.tet.2015.02.032

"A Cp*CoI2-dimer as A Precursor for Cationic Co(III)-catalysis: Application to C-H Phosphoramidation of Indoles"

Sun, B.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Chem. Commun. 2015, 51, 4659. DOI: 10.1039/C4CC10284C

2014

"Regiodivergent Kinetic Resolution of Terminal and Internal rac-Aziridines with Malonates under Dinuclear Schiff Base Catalysis"

Xu, Y.; Kaneko, K.; Kanai, M.; Shibasaki, M.; Matsunaga, S.
J. Am. Chem. Soc. 2014, 136, 9190. DOI: 10.1021/ja5039165

"Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C-H Alkenylation/Annulation Sequence"

Ikemoto, H.; Yoshino, T.; Sakata, K.; Matsunaga, S.; Kanai, M.
J. Am. Chem. Soc. 2014, 136, 5424. DOI: 10.1021/ja5008432
*Featured by SJN news.

"Air-Stable Carbonyl(pentamethylcyclopentadienyl)cobalt Diiodide Complex as a Precursor for Cationic (Pentamethylcyclopentadienyl)cobalt(III) Catalysis: Application for Directed C-2 Selective C-H Amidation of Indoles"

Sun, B.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Adv. Synth. Catal. 2014, 356, 1491. DOI: 10.1002/adsc.201301110
*Selected as cover picture.

"Cobalt-Catalyzed C-4 Selective Alkylation of Quinolines"

Yamamoto, S.; Saga, Y.; Andou, T.; Matsunaga, S.; Kanai, M.
Adv. Synth. Catal. 2014, 356, 401. DOI: 10.1002/adsc.201300991

"Enantioselective Synthesis of Spirooxindoles via Direct Catalytic Asymmetric Aldol-Type Reaction of Isothiocyanato Oxindoles"

Kato, S.; Kanai, M.; Matsunaga, S.
Heterocycles 2014, 88, 475. DOI: 10.3987/COM-13-S(S)60

"Recent advances in cooperative bimetallic asymmetric catalysis: dinuclear Schiff base complexes"

Matsunaga, S.; Shibasaki, M.
Chem. Commun. 2014, 50, 1044. DOI: 10.1039/C3CC47587E

2013

"Rh-Catalyzed Aldehyde-Aldehyde Cross-Aldol Reaction under Base-Free Conditions: In-Situ Aldehyde-Derived Enolate Formation through Orthogonal Activation"

Lin, L.; Yamamoto, K.; Matsunaga, S.; Kanai, M.
Chem. Asian J. 2013, 8, 2974. DOI: 10.1002/asia.201300928

"Structure-activity relationship study of novel iminothiadiazolo-pyrimidinone antimicrobial agents"

Paudel, A.; Kaneko, K.; Watanabe, A.; Matsunaga, S.; Kanai, M.; Hamamoto, H.; Sekimizu, K.
J. Antibiot. 2013, 66, 663. DOI: 10.1038/ja.2013.69

"Cp*CoIII-Catalyzed C2-Selective Addition of Indoles to Imines"

Yoshino, T.; Ikemoto, H.; Matsunaga, S.; Kanai, M.
Chem. Eur. J. 2013, 19, 9142. DOI: 10.1002/chem.201301505

"Sultam Synthesis via Cu-Catalyzed Intermolecular Carboamination of Alkenes with N-Fluorobenzenesulfonimide"

Kaneko, K.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Org. Lett. 2013, 15, 2502. DOI: 10.1021/ol4009848

"Catalytic Asymmetric Synthesis of Spirooxindoles via Addition of Isothiocyanato Oxindoles to Aldehydes Under Dinuclear Nickel Schiff Base Catalysis"

Kato, S.; Kanai, M.; Matsunaga, S.
Chem. Asian J. 2013, 8, 1768. DOI: 10.1002/asia.201300251

"A Cationic High-Valent Cp*CoIII Complex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed C-H Bond Activation"

Yoshino, T. Ikemoto, H.; Matsunaga, S.; Kanai, M.
Angew. Chem. Int., Ed. 2013, 52, 2207. DOI: 10.1002/anie.201209226

"Multimetallic Schiff Base Complexes as Cooperative Asymmetric Catalysts"

Matsunaga, S.; Shibasaki, M.
Synthesis 2013, 45, 421. DOI: 10.1055/s-0032-1316846

2012

"Rhodium-Catalyzed Cross-Aldol Reaction: In Situ Aldehyde-Enolate Formation from Allyloxyboranes and Primary Allylic Alcohols"

Lin, L.; Yamamoto, K.; Matsunaga, S.; Kanai, M.
Angew. Chem. Int., Ed. 2012, 51, 10275. DOI: 10.1002/anie.201205680

"Direct Catalytic Asymmetric Vinylogous Michael Reaction of α,β-Unsaturated γ-Butyrolactam under Dinuclear Nickel Schiff Base Catalysis"

Tanabe, H.; Xu, Y.; Sun, B.; Matsunaga, S.; Shibasaki, M.
Heterocycles 2012, 86, 611. DOI: 10.3987/COM-12-S(N)58

"Enantioselective Synthesis of 2,2-Disubstituted Terminal Epoxides via Catalytic Asymmetric Corey-Chaykovsky Epoxidation of Ketones"

Sone, T.; Yamaguchi, A.; Matsunaga, S.; Shibasaki, M.
Molecules 2012, 17, 1617. DOI: 10.3390/molecules17021617 (open access)

"Catalytic Asymmetric Amination of Oxindoles under Dinuclear Nickel Schiff Base Catalysis"

Mouri, S.; Chen, Z.; Matsunaga, S.; Shibasaki, M.
Heterocycles 2012, 84, 879. DOI: 10.3987/COM-11-S(P)66

"Catalytic Asymmetric Synthesis of Spirooxindoles by a Mannich-Type Reaction of Isothiocyanato Oxindoles"

Kato, S.; Yoshino, T.; Shibasaki, M.; Kanai, M.; Matsunaga, S.
Angew. Chem., Int. Ed. 2012, 51, 7007. DOI: 10.1002/anie.201203005

"Mg-catalyzed Enantioselective Benzylic C-H Bond Functionalization of Isoindolinones: Addition to Imines"

Suzuki, Y.; Kanai, M.; Matsunaga, S.
Chem. Eur. J. 2012, 18, 7654. DOI: 10.1002/chem.201200821

"Lewis Acid Catalyzed Benzylic C-H Bond Functionalization of Azaarenes; Addition to Imines and Enones"

Komai, H.; Yoshino, T.; Matsunaga, S.; Kanai, M.
Synthesis 2012, 44, 2185. DOI: 10.1055/s-0031-1291041

"Catalytic Asymmetric Total Synthesis of Chimonanthine, Folicanthine, and Calycanthine through Double Michael Reaction of Bisoxindole"

Mitsunuma, H.; Shibasaki, M.; Kanai, M.; Matsunaga, S.
Angew. Chem., Int. Ed. 2012, 51, 5217. DOI: 10.1002/anie.201201132

2011年以前(PDF)

アクセス

薬品製造化学研究室
北海道大学大学院
薬学研究院
〒060-0812
札幌市北区北12条西6丁目
TEL:011-706-3236
FAX: 011-706-4981

↑ PAGE TOP