発表論文　2007年

1. 1.Hirano, S.; Ichikawa, S.; Matsuda, A.
   Development of a highly β-selective ribosylation reaction without using neighboring group participation: Total synthesis of (+)-caprazol, a core structure of caprazamycins.
   J. Org. Chem. 2007, 72, 9936-9946. DOI: 10.1021/jo701699h
          

   

   
   
   
2. 2.Inoue, N.; Shionoya, A.; Minakawa, N.; Ogawa, N.; Matsuda, A.
   Amplification of 4´-thioDNA in the presence of 4´-thio-dTTP and 4´-thio-dCTP, and 4´-thioDNA-derected transcription in vitro and in mammalian cells.
   J. Am. Chem. Soc. 2007, 129, 15424-15425. DOI: 10.1021/ja075953c
          

   

   
   
   
3. 3.Hoshika, S.; Minakawa, N.; Shionoya, A.; Imada, K.; Ogawa, N.; Matsuda, A.
   Study of modification pattern-RNAi activity relationships using siRNAs modified with 4´-thioribonucleosides; finding an effective modification irrespective of target sequence.
   ChemBioChem, 2007, 8, 2133-2138. DOI: 10.1002/cbic.200700342
          

   

   
   
   
4. 4.Murata, S.; Mizumura, Y.; Hino, K.; Ueno, Y.; Ichikawa, S.; Matsuda, A.
   Modular bent DNAs: A new class of artificial DNAs with a protein binding ability.
   J. Am. Chem. Soc. 2007, 129, 10300-10301. DOI: 10.1021/ja071335k
          

   

   
   
   
5. 5.Yasui, H.; Inanami, O.; Asanuma, T.; Iizuka, D.; Nakajima, T.; Kon, Y.; Matsuda, A.; Kuwabara, M.
   Treatment combining X irradiation and a ribonucleoside anticancer drug, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine, synergistically suppresses the growth of tumor cells transplanted in mice.
   Int, J. Rad. Oncol. Biol. Phys. 2007, 68, 218-228.

   

   DOI:10.1016/j.ijrobp.2006.12.061 
   

6. 6.
   
   

7. 7.Ohtawa, M.; Ichikawa, S.; Teishikata, Y.; Fujimuro, M.; Yokosawa, H.; Matsuda, A.
   9-(2-C-Cyano-2-deoxy-β-D-arabino-pentofuranosyl)guanine (CNDAG), a potent antitumor agent against B-lymphoma infected with Kaposi’s sarcoma-associated Herpesvirus (KSHV).
   J. Med. Chem. 2007, 50, 2007-2010. DOI: 10.1021/jm070032y
          

   

   
   
   

8. 8.Kazuno, H.; Shimamoto, Y.; Tsujimoto, H.; Fukushima, M.; Matsuda, A.; Sasaki, T.
   Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil.
   Oncology Rep. 2007, 17, 1453-1460. Abstract
   
   

9. 9.Juan, E. C. M.; Kondo, J.; Kurihara, T.; Ito, T.; Ueno, Y.; Matsuda, A.; Takenaka, A.
   Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)-carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules.
   Nucleic Acids Res. 2007, 35, 1969-1977. DOI: 10.1093/nar/gkl821
   
   

10. 10.Kudoh, T.; Murayama, T.; Matsuda, A.; Shuto, S.
    Substitution at the 8-position of 3´´-deoxy-cyclic ADP-carbocyclic-ribose, a highly potent Ca2+-mobilizing agent, provides partial agonist.
    Bioorg. Med. Chem. 2007, 15, 3032-3040. DOI: 10.1016/j.bmc.2007.02.001
           
    

11. 11.Hirano, S.; Ichikawa, S.; Matsuda, A.
    Total synthesis of (+)-FR-900493 and establishment of its absolute stereochemistry.
    Tetrahedron, 2007, 63, 2798-2804. DOI: 10.1016/j.tet.2007.01.055
           

    

    
    
    

12. 12.Ichikawa, S.; Matsuda, A.
    Nucleoside natural products and related analogs with potential therapeutic properties as antibacterial and antiviral agents.
    Expert Opin. Ther. Patents 2007, 17, 487-498. DOI: 10.1517/13543776.17.5.487
    
    

13. 13.Endo, Y.; Obata, T.; Nomura, M.; Fukushima, M.; Yamada, Y.; Matsuda, A.; Sasaki, T.
    Development of an antitumor adenosine analog, 3´-ethynyladenosine.
    Nucleosides, Nucleotides & Nucleic Acids 2007, 26, 691-694. DOI: 10.1080/15257770701490654
    
    

14. 14.松田　彰
    分子構造から考える薬物の作用機序 (3) 抗A型およびB型インフルエンザウイルス薬：ザナミビル水和物とリン酸オセルタミビル．
    医薬ジャーナル, 2007, 43, 1-5.
    
    

15. 15.猪上　尚徳，松田　彰
    アプタマーと遺伝子暗号の拡張．
    化学, 2007, 62, 64-65.
    
    

16. 16.松田　彰，南川　典昭
    核酸医薬の創製をめざして．
    『バイオとナノの融合II，新生命科学への応用』, 北海道大学COE研究成果編集委員会編, 2007, pp187-199, 北海道大学.
    
    

17. 17.南川　典昭，松田　彰
    スーパー核酸：4´-チオ核酸の合成から核酸医薬開発に向けた基礎研究の展開．
    化学フロンティア『創薬をめざす有機合成戦略：進化する医薬品づくり』, 宍戸宏造，新藤充編, 2007, pp157-164, 化学同人.