発表論文　2006年

1. 1.Hikishima, S.; Minakawa, N.; Kuramoto, K.; Ogata, S.; Matsuda, A.
   Synthesis and characterization of oligodeoxynucleotides containing naphthyridine: imidazopyridopyrimidine base pairs at their sticky ends. Application as  thermally stabilized decoy molecules.
   ChemBioChem 2006, 7, 1970-1975. DOI: 10.1002/cbic.200600318
          

   

   
   
   

2. 2.Kamiya, H.; Cadena-Amaro, C.; Dugueacute, L.; Yakushiji, H.; Minakawa, N.; Matsuda, A.; Pochet, S.; Nakabeppu, Y.; Harashima, H.
   Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein.
   J. Biochem. 2006, 140, 843-849. DOI: 10.1093/jb/mvj214
   
   

3. 3.Takahashi, H.; Inanami, O.; Ohta, T.; Matuda, A.; Kuwabara, M.
   Lipid raft disruption prevents apoptosis induced by 2-chloro-2´-deoxyadenosine (cladribine) in leukemia cell lines.
   Leuk. Res. 2006, 30, 1555-1561. DOI: 10.1016/j.leukres.2006.04.008
   
   

4. 4.Kodama, T.; Matsuda, A.; Shuto, S.
   Synthesis of 1´-fluorouracil nucleosides as potential antimetabolites.
   Tetrahedron, 2006, 62, 10011-10017. DOI: 10.1016/j.tet.2006.07.101 
          

   

   
   
   

5. 5.Watanabe, M.; Kazuta, Y.; Hayashi, H.; Yamada, S.; Matsuda, A.; Shuto, S.
   Stereochemistry deversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonist with an imidazolylcyclopropane structure.
   J. Med. Chem. 2006, 49, 5587-5596. DOI: 10.1021/jm0603318
          
   

6. 6.Mochizuki, T.; Kondo, Y.; Abe, H.; Tovey, S.; Dedos, S. G.; Taylor, C. W.; Paul, M.; Potter, B. V. L.; Matsuda, A.; Shuto, S.
   Synthesis of adenophostin A analogues conjugating an aromatic group at the 5´-position as potent IP3 receptor ligands.
   J. Med. Chem. 2006, 49, 5750-5758. DOI: 10.1021/jm060310d
          
   

7. 7.Inoue, N.; Minakawa, N.; Matsuda, A.
   Synthesis and properties of 4´-thioDNA: unexpected RNA-like behavior of 4´-thioDNA.
   Nucleic Acids Res. 2006, 34, 3476-3483. DOI: 10.1093/nar/gkl491
   
   

8. 8.Sakaguchi, N.; Hirano, S.; Matuda, A.; Shuto, S.
   Radical reaction with 2-bromobenzylidene group, a protecting/radical-translocating group for the 1,6-radical hydrogen transfer reaction.
   Org. Lett. 2006, 8, 3291-3294. DOI: 10.1021/ol061162o      
   
   

9. 9.Kudoh, T.; Murayama, T.; Ogawa, Y.; Matsuda, A.; Shuto, S
   Synthesis of cyclic ADP-carbocyclic-xylose and its 3´-O-methyl analogue as stable and potent Ca2+ mobilizing agents.
   Nucleosides, Nucleotides & Nucleic Acids 2006, 25, 583-599. DOI: 10.1080/15257770600685867
   
   

10. 10.Kamiya, H.; Ito, M.; Ochiai, H.; Matsuda, A.; Harashima, H.
    Transient expression of Drosophila melanogaster deoxynucleoside kinase gene enhances cytotoxicity of nucleoside analogs.
    Nucleosides, Nucleotides & Nucleic Acids 2006, 25, 553-560. DOI: 10.1080/15257770600685784
    
    

11. 11.Kodama, T.; Shuto, S.; Matsuda, A.
    Synthesis of pyrimidine 1´-fluoronucleosides.
    Tetrahedron Lett. 2006, 47, 4429-4432.

    

    DOI: 10.1016/j.tetlet.2006.04.099
           

    

    
    
    

12. 12.Terauchi, M.; Abe, H.; Tovey, S. C.; Dedos, S. G.; Taylor, C. W.; Paul, M.; Trusselle, M.; Potter, B. V. L.; Matsuda, A.; Shuto, S.
    A systematic study of C-glucoside triphosphates as myo-inositol triphosphate receptor ligands. Synthesis of β-C-glucoside triphosphates based on the conformational restriction strategy.
    J. Med. Chem. 2006, 49, 1900-1909. DOI: 10.1021/jm051039n    
    
    

13. 13.Mochizuki, T.; Kondo, Y.; Abe, H.; Taylor, C. W.; Potter, B. V. l.; Matsuda, A.; Shuto, S.
    Design and synthesis of 5´-deoxy-5´-phenyladenophostin A, a highly potent IP3 receptor ligand.
    Org. Lett. 2006, 8, 1455-1458. DOI: 10.1021/ol0602710
           
    

14. 14.Ichikawa, S.; Minakawa, N,; Shuto, S.; Tanaka, M.; Sasaki, T.; Matsuda, A.
    Synthesis  of 3´-β-carbamoylmethylcytidine (CAMC) and its derivatives as potential antitumor agents.
    Org. Biomol. Chem. 2006, 4, 1284-1296. DOI: 10.1039/B517602F
           

    

    
    
    

15. 15.Minakawa, N.; Kuramoto, K.; Hikishima, S.; Matsuda, A.
    Four hydrogen-bonding motifs in oligonucleotides.
    ARKIVOC, 2006, 326-337. Abstract
    
    

16. 16.Shibata, A.; Ueno, Y.; Shinbo, K.; Nakanishi, M,; Matsuda, A.; Kitade, Y.
    Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein.
    Bioorg. Med. Chem. Lett. 2006, 16, 1410-1413.

    

    DOI:10.1016/j.bmcl.2005.11.036
           
    

17. 17.桑原　幹典、稲波　修、安井　博宣、飯塚　大輔、松田　彰
    エチニルシチジンの放射線増感効果．
    癌の臨床, 2006, 52, 31-36.