発表論文　2012年

1. 1.Okamoto, K.; Sakagami, M.; Feng, F.; Togame, H.; Takemoto, H.; Ichikawa, S.; Matsuda, A.
   Total Synthesis and Biological Evaluation of Pacidamycin D and Its 3´-Hydroxy Analogue.
   J. Org. Chem. 2012, 77, 1367-1377. DOI: 10.1021/jo202159q
   

   

   
   

2. 2.Takahashi, M.; Nagai, C.; Hatakeyama, H.; Minakawa, N.; Harashima, H.; Matsuda, A.
   Intracellular stability of 2′-OMe-4′-thioribonucleoside modified siRNA leads to long-term RNAi effect.
   Nucleic Acids Res. 2012, 40, 5787-5793. DOI: 10.1093/nar/gks204
   
   

3. 3.Shibata, A.; Ueno, Y.; Iwata, M.; Wakita, H.; Matsuda, A.; Kitade, Y.
   Double-stranded oligonucleotides containing 5-aminomethyl-2′-deoxyuridine form thermostable anti-parallel triplexes with single-stranded DNA or RNA.
   Bioorg. Med. Chem. Lett. 2012, 22, 2681-2683. DOI: 10.1016/j.bmcl.2012.03.024
   

4. 4.Okamoto, K.; Sakagami, M.; Feng, F.; Takahashi, F.; Uotani, K.; Togame, H.; Takemoto, H.; Ichikawa, S.; Matsuda, A.
   Synthesis of pacidamycin analogues via an Ugi-multicomponent reaction.
   Bioorg. Med. Chem. Lett. 2012, 22, 4810-4815. DOI: 10.1016/j.bmcl.2012.05.050