Graduate School of Pharmaceutical Sciences, Hokkaido University
Laboratory for Bioanalysis and Molecular Imaging
Publications

Research Achievements

Original Article

  1. Goto Y, Ando K, Takakura H, Nakajima K, Kobayashi M, Inanami O, Taketsugu T, Ogawa M. Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer. J Photochem Photobiol. 2024 20, 100230 DOI 10.1016/j.jpap.2024.100230
  2. Inanami O, Hiraoka W, Goto Y, Takakura H, Ogawa M. EPR Characterisation of Phthalocyanine Radical Anions in Near-Infrared Photocleavage of the Hydrophilic Axial Ligand of a Photoimmunotherapeutic Reagent, IR700. ChemPhotoChem 2022, 6 (1), e202100172. DOI 10.1002/cptc.202100172 (Cover Profile:DOI 10.1002/cptc.202100277)
  3. Takakura H, Matsuhiro S, Kobayashi M, Goto Y, Harada M, Taketsugu T, Ogawa M. Axial-ligand-cleavable silicon phthalocyanines triggered by near-infrared light toward design of photosensitizers for photoimmunotherapy. J Photochem Photobiol A: Chem 2022, 426 (1), 113749. DOI 10.1016/j.jphotochem.2021.113749
  4. Kato T, Okada R, Goto Y, Furusawa A, Inagaki F, Wakiyama H, Furumoto H, Daar D, Turkbey B, Choyke PL, Takakura H, Inanami O, Ogawa M, Kobayashi H. Electron Donors Rather Than Reactive Oxygen Species Needed for Therapeutic Photochemical Reaction of Near-Infrared Photoimmunotherapy. ACS Pharmacol Transl Sci 2021, 4 (5), 1689-1701. PMID 34661083
  5. Takakura H, Goto Y, Kitamura A, Yoshihara T, Tobita S, Kinjo M, Ogawa M. Analysis of the triplet-state kinetics of a photosensitizer for photoimmunotherapy by fluorescence correlation spectroscopy. J Photochem Photobiol A: Chem 2021, 408, 113094. DOI 10.1016/j.jphotochem.2020.1130942
  6. Kobayashi M, Harada M, Takakura H, Ando K, Goto Y, Takao T, Ogawa M, Taketsugu T. Theoretical and Experimental Studies on the Near-Infrared Photoreaction Mechanism of a Silicon Phthalocyanine Photoimmunotherapy Dye: Photoinduced Hydrolysis by Radical Anion Generation. Chempluschem 2020, 85, 1-6. PMID 32449613 (Cover Profile:PMID 32830450)