Laboratory of Drug Discovery, Center for Research and Education on Drug Discovery

Publications

Presented Paper 2023

  1. Solid-Phase Synthesis of Nannocystin Ax and Its Analogues

    Daiki Miyakita, Kohei Kawanishi, Akira Katsuyama, Kazuki Yamamoto, Fumika Yakushiji, Satoshi Ichikawa

    J. Org. Chem. 2023, 88, 11367.

    DOI: 10.1021/acs.joc.3c01189

    images_medium_jo3c01189_0007

  2. Development of a Natural Product Optimization Strategy for inhibitors against the cell wall synthesis enzyme MraY, a promising antibacterial target

    Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Ruddarraju Radhakrishnam Raju, Daichi Kazumori,  Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Sin-ichi Yokota, Seol-Yong Lee, Satoshi Ichikawa

    ChemRxiv 2023

    DOI: 10.26434/chemrxiv-2023-2w41l

  3. Discovery of Biologically Optimized Polymyxin Derivatives Facilitated by Peptide Scanning and In Situ Screening Chemistry
    Rintaro Kaguchi, Akira Katsuyama, Toyotaka Sato, Satoshi Takahashi, Motohiro Horiuchi, Shin-ichi Yokota, Satoshi Ichikawa
    J. Am. Chem. Soc. 2023, 145, 3665.
  4. Solid-Phase Total Synthesis of Sandramycin and Its Analogues
    Yuya Komatani, Kyoka Momosaki, Akira Katsuyama, Kazuki Yamamoto, Rintaro Kaguchi, Satoshi Ichikawa
    Org. Lett. 2023, 25, 543.
    Figure 1

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