Publication 2021

Professor Sugawara

1. Tsutsumi T, Imai S, Kashiwagi H, Sato Y, Sugawara M, Takekuma Y.:
   Investigation of the risk factors of vomiting during linezolid therapy: a retrospective observational study.
   Eur J Clin Pharmacol. 2021 Sep 28. doi: 10.1007/s00228-021-03221-x. Epub ahead of print. PMID: 34581841.
2. Imai S, Kashiwagi H, Sato Y, Miyai T, Sugawara M, Takekuma Y. :
   Factors affecting creatine phosphokinase elevation during daptomycin therapy using
   a combination of machine learning and conventional methods. Br J Clin Pharmacol. 2021 Aug 26. doi: 10.1111/bcp.15063. Epub ahead of print. PMID: 34436795.
3. Yamashita S, Imai S, Momo K, Kashiwagi H, Sato Y, Sugawara M, Takekuma Y.:
   Investigation of the Real-World Situation and Risk Factors Associated with Olanzapine Prescribed to
   Diabetes Patients by Using a Japanese Claims Database. Biol Pharm Bull. 2021;44(8):1151-1155. doi: 10.1248/bpb.b21-00170. PMID: 34334500.
4. Aoyama T, Kuriyama H, Sato Y, Imai S, Kashiwagi H, Sugawara M, Takekuma Y.:
   cAMP Signaling Pathway Prevents Dasatinib-Induced Vascular Hyperpermeability.
   Biol Pharm Bull. 2021;44(8):1101-1110. doi: 10.1248/bpb.b21-00270. PMID: 34334496.
5. Imai S, Momo K, Kashiwagi H, Sato Y, Miyai T, Sugawara M, Takekuma Y.:
   A cross-sectional survey of hospitalization and blood tests implementation status in patients
   who received tolvaptan under 75 years of age using a Japanese claims database. Expert Opin Drug Saf. 2021 Oct;20(10):1257-1266. doi: 10.1080/14740338.2021.1951219. Epub 2021 Jul 19. PMID: 34225550.
6. Nashimoto S, Yagi S, Takeda N, Nonaka M, Takekuma Y, Sugawara M, Sato Y.:
   A new system to evaluate characteristics of Niemann-Pick C1 Like 1-mediated cholesterol transport using
   Xenopus laevis oocytes. Biochim Biophys Acta Biomembr. 2021 Feb 1;1863(2):183508. doi: 10.1016/j.bbamem.2020.183508. Epub 2020 Nov 11. PMID: 33188743.
7. Sato Y, Yamaguchi K, Ogawa M, Takekuma Y, Sugawara M.
   An imaging approach for determining the mechanism of enhancement of intestinal absorption of an L-theanine supplement. PLoS One 16(6), e0253066 (2021).

 

Professor Wakimoto

1. T. Jomori, K. Matsuda, Y. Egami, I. Abe, A. Takai, T. Wakimoto,
   Insights into phosphatase-activated chemical defense in a marine sponge holobiont.
   RSC Chem. Biol. 2, 1600-1607 (2021)
2. 1: Matsuda K, Fujita K, Wakimoto T. PenA, a penicillin-binding protein-type
   thioesterase specialized for small peptide cyclization. J Ind Microbiol
   Biotechnol. 2021 Jun 4;48(3-4):kuab023. doi: 10.1093/jimb/kuab023. PMID:
   33713128
3. M. Hoshino, S. F. Hiruta, M. E. Croce, M. Kamiya, T. Jomori, T. Wakimoto, K. Kogame, Geographical parthenogenesis in the brown alga Scytosiphon lomentaria (Scytosiphonaceae): Sexuals in warm waters and parthenogens in cold waters. Mol. Ecol. in press (2021)
4. C. S. Phan, K. Matsuda, N. Ballo, K. Fujita, T. Wakimoto, T. Okino, Argicyclamides A–C unveil enzymatic basis for guanidine bis-prenylation. J. Am. Chem. Soc. 143, 10083-10087 (2021)
5. I. F. M. Rumengan, V. I. Y. Roring, J. R. Haedar, M. S. Siby, A. H. Luntungan, B. J. Kolondam, A. Uria, T. Wakimoto, Ascidian-associated photosymbionts from Manado, Indonesia: secondary metabolites, bioactivity simulation, and biosynthetic insight. Symbiosis, 84, 1-12 (2021)

Professor Maenaka

1: Nakamura M, Uemura K, Saito-Tarashima N, Sato A, Orba Y, Sawa H, Matsuda A, Maenaka K, Minakawa N. Synthesis and anti-dengue virus activity of 5-ethynylimidazole-4-carboxamide (EICA) nucleotide prodrugs. Chem Pharm Bull (Tokyo). 2021 Dec 25. doi: 10.1248/cpb.c21-01038. Epub ahead of print. PMID: 34955490

2: Hasegawa T, Imamura RM, Suzuki T, Hashiguchi T, Nomura T, Otsuguro S, Maenaka K, Sasaki M, Orba Y, Sawa H, Sato A, Okabe T, Nagano T, Kojima H. Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors. Chem Pharm Bull (Tokyo). 2021 Dec 21. doi: 10.1248/cpb.c21-01003. Epub ahead of print. PMID: 34937844.

3: Kuroki K, Fukuhara H, Tadokoro T, Maenaka K. Low-Cost Cell-Surface-Mimic Analysis of Ligand Interactions of Biotinylated Immune Receptors Using Surface Plasmon Resonance. Methods Mol Biol. 2022;2421:21-35. doi: 10.1007/978-1-0716-1944-5_2. PMID: 34870809.

4: Yumoto K, Arisaka T, Okada K, Aoki K, Ose T, Masatani T, Sugiyama M, Ito N, Fukuhara H, Maenaka K. Characterization of Single-Chain Fv Fragments of Neutralizing Antibodies to Rabies Virus Glycoprotein. Viruses. 2021 Nov 19;13(11):2311. doi: 10.3390/v13112311. PMID: 34835117; PMCID: PMC8624154.

5: Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito- Tarashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K. 5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2. iScience. 2021 Oct 22;24(10):103120. doi: 10.1016/j.isci.2021.103120. Epub 2021 Sep 11. PMID: 34541466; PMCID: PMC8433052.

6: Onodera T, Kita S, Adachi Y, Moriyama S, Sato A, Nomura T, Sakakibara S, Inoue T, Tadokoro T, Anraku Y, Yumoto K, Tian C, Fukuhara H, Sasaki M, Orba Y, Shiwa N, Iwata N, Nagata N, Suzuki T, Sasaki J, Sekizuka T, Tonouchi K, Sun L, Fukushi S, Satofuka H, Kazuki Y, Oshimura M, Kurosaki T, Kuroda M, Matsuura Y, Suzuki T, Sawa H, Hashiguchi T, Maenaka K, Takahashi Y. A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site. Immunity. 2021 Oct 12;54(10):2385-2398.e10. doi: 10.1016/j.immuni.2021.08.025. Epub 2021 Aug 24. PMID: 34508662; PMCID: PMC8382582.

7: Tanikawa Y, Kanemura S, Ito D, Lin Y, Matsusaki M, Kuroki K, Yamaguchi H, Maenaka K, Lee YH, Inaba K, Okumura M. Ca<sup>2+</sup> Regulates ERp57-Calnexin Complex Formation. Molecules. 2021 May 11;26(10):2853. doi: 10.3390/molecules26102853. PMID: 34064874; PMCID: PMC8151781.

8: Ohashi H, Watashi K, Saso W, Shionoya K, Iwanami S, Hirokawa T, Shirai T, Kanaya S, Ito Y, Kim KS, Nomura T, Suzuki T, Nishioka K, Ando S, Ejima K, Koizumi Y, Tanaka T, Aoki S, Kuramochi K, Suzuki T, Hashiguchi T, Maenaka K, Matano T, Muramatsu M, Saijo M, Aihara K, Iwami S, Takeda M, McKeating JA, Wakita T. Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatment. iScience. 2021 Apr 23;24(4):102367. doi: 10.1016/j.isci.2021.102367. Epub 2021 Mar 26. PMID: 33817567; PMCID: PMC7997640.

9: Tomita Y, Matsuyama S, Fukuhara H, Maenaka K, Kataoka H, Hashiguchi T, Takeda M. The Physiological TMPRSS2 Inhibitor HAI-2 Alleviates SARS-CoV-2 Infection. J Virol. 2021 May 24;95(12):e00434-21. doi: 10.1128/JVI.00434-21. PMID: 33789993; PMCID: PMC8315915.

10: Yoshida T, Yamagata A, Imai A, Kim J, Izumi H, Nakashima S, Shiroshima T, Maeda A, Iwasawa-Okamoto S, Azechi K, Osaka F, Saitoh T, Maenaka K, Shimada T, Fukata Y, Fukata M, Matsumoto J, Nishijo H, Takao K, Tanaka S, Okabe S, Tabuchi K, Uemura T, Mishina M, Mori H, Fukai S. Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice. Nat Commun. 2021 Mar 23;12(1):1848. doi: 10.1038/s41467-021-22059-6. PMID: 33758193; PMCID: PMC7988105.

11: Uemura K, Sasaki M, Sanaki T, Toba S, Takahashi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A. MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2. Sci Rep. 2021 Mar 8;11(1):5376. doi: 10.1038/s41598-021-84882-7. PMID: 33686154; PMCID: PMC7940632.

Professor Kihara

1. Sawai M, Watanabe K, Tanaka K, Kinoshita W, Otsuka K, Miyamoto M, Sassa T, Kihara A. Diverse meibum lipids produced by Awat1 and Awat2 are important for stabilizing tear film and protecting the ocular surface. iScience, 24 (5) 102478 (2021)
2. Sassa T, Imai Y, Kihara A, Yamanishi K. Protein-bound ceramide levels in the epidermis of transglutaminase 1-deficient mice. J. Dermatol., in press (2021)
3. Nojiri K, Fudetani S, Arai A, Kitamura T, Sassa T, Kihara A. Impaired skin barrier function due to reduced ω-O-acylceramide levels in a mouse model of Sjogren-Larsson syndrome. Mol. Cell. Biol., in press (2021)
4. Sato Y, Yamaguchi K, Ogawa M, Takekuma Y, Sugawara M. An imaging approach for determining the mechanism of enhancement of intestinal absorption of an L-theanine supplement. PLoS One 16(6), e0253066 (2021).
5. Watanabe K, Yoshida M, Okumura T, Sassa T, Kihara A, Uchiyama A. Improvement of Evaporative Dry Eye With Meibomian Gland Dysfunction in Model Mice by Treatment With Ophthalmic Solution Containing Mineral Oil. Transl Vis Sci Technol. 2021 Apr 1;10(4):21. doi: 10.1167/tvst.10.4.21. PMID: 34003999; PMCID:
   PMC8083063.
6. Takeda K, Yano K, Yamada K, Kihara A. Amlexanox enhances the antitumor effect of anti-PD-1 antibody. Biochem Biophys Res Commun. 2021 Jun 30;560:1-6. doi:10.1016/j.bbrc.2021.04.126. Epub 2021 May 6. PMID: 33965784.
7. Goto H, Miyamoto M, Kihara A. Direct uptake of sphingosine-1-phosphate independent of phospholipid phosphatases. J Biol Chem. 2021 Jan-Jun;296:100605. doi: 10.1016/j.jbc.2021.100605. Epub 2021 Mar 27. PMID: 33785361; PMCID:PMC8093947.

 

Professor Ogawa

1: Obata H, Minegishi K, Nagatsu K, Ogawa M, Zhang MR. Synthesis of no-carrier- added [<sup>188, 189, 191</sup>Pt]cisplatin from a cyclotron produced <sup>188, 189, 191</sup>PtCl<sub>4</sub><sup>2-</sup> complex. Sci Rep. 2021 Apr 14;11(1):8140. doi: 10.1038/s41598-021-87576-2. PMID: 33854142; PMCID: PMC8046966.

2: Obata H, Tsuji AB, Sudo H, Sugyo A, Minegishi K, Nagatsu K, Ogawa M, Zhang MR. In Vitro Evaluation of No-Carrier-Added Radiolabeled Cisplatin ([<sup>189, 191</sup>Pt]cisplatin) Emitting Auger Electrons. Int J Mol Sci. 2021 Apr 28;22(9):4622. doi: 10.3390/ijms22094622. PMID: 33924843; PMCID: PMC8124180.

3: Takakura H, Sato H, Nakajima K, Suzuki M, Ogawa M. In Vitro and In Vivo Cell Uptake of a Cell-Penetrating Peptide Conjugated with Fluorescent Dyes Having Different Chemical Properties. Cancers (Basel) 13(9) (2021).

4: Takakura H, Goto Y, Kitamura A, Yoshihara T, Tobita S, Kinjyo M, Ogawa M. Analysis of the triplet-state kinetics of a photosensitizer for photoimmunotherapy by fluorescence correlation spectroscopy. Journal of Photochemistry and Photobiology A: Chemistry 408(113094 (2021).

5: Sato Y, Yamaguchi K, Ogawa M, Takekuma Y, Sugawara M. An imaging approach for determining the mechanism of enhancement of intestinal absorption of an L-theanine supplement. PLoS One 16(6), e0253066 (2021).

6: Ogawa M, Takakura H. Photoimmunotherapy: A new cancer treatment using photochemical reactions. Bioorg Med Chem 43(116274 (2021).

7: Matsuoka K, Obata H, Nagatsu K, Kojima M, Yoshino T, Ogawa M, Matsunaga S. Transition-metal-free nucleophilic (211)At-astatination of spirocyclic aryliodonium ylides. Org Biomol Chem 19(25), 5525-5528 (2021).

8: Hirata H, Kuwatani M, Nakajima K, Kodama Y, Yoshikawa Y, Ogawa M, Sakamoto N. Near-infrared photoimmunotherapy (NIR-PIT) on cholangiocarcinoma using a novelcatheter device with light emitting diodes.Cancer Sci 112(2), 828-838 (2021).

9: Suzuki M, Katayama T, Suzuki C, Nakajima K, Magata Y, Ogawa M. Uptake of nicotinic acetylcholine receptor imaging agent is reduced in the pro-inflammatory macrophage. Nuclear Medicine and Biology 102-103, 44-55, 2021

10: Inanami O, Hiraoka W, Goto Y, Takakura H, Ogawa M. EPR Characterisation of Phthalocyanine Radical Anions in Near‐Infrared Photocleavage of the Hydrophilic Axial Ligand of a Photoimmunotherapeutic Reagent, IR700.ChemPhotoChem 6, e202100172, 2022

11: Nakajima K, Homma M, Suzuki M, Yokouchi Y, Matsuda T, Takakura H, Hirata K, Kuge Y, Ogawa M. Reduction of tumor hypoxia by anti-PD-1 therapy assessed using pimonidazole and [18F]FMISO. Nuclear Medicine and Biology 108-109, 85-92, 2022

Professor Ichikawa

1: Konishi H, Isozaki S, Kashima S, Moriichi K, Ichikawa S, Yamamoto K, Yamamura C, Ando K, Ueno N, Akutsu H, Ogawa N, Fujiya M. Probiotic Aspergillus oryzae produces anti-tumor mediator and exerts anti-tumor effects in pancreatic cancer through the p38 MAPK signaling pathway. Sci Rep. 2021 May 26;11(1):11070. doi: 10.1038/s41598-021-90707-4. PMID: 34040123; PMCID: PMC8154913.

2: Probiotic Aspergillus oryzae produces the antitumor mediator and exhibits antitumor effects in pancreatic cancer through p38 MAPK signaling pathway. Konishi, Hiroaki*; Isozaki, Shotaro; Kashima, Shin; Moriichi, Kentaro; Ichikawa, Satoshi; Yamamoto Kazuki; Yamamura, Chikage; Ando, Katsuyoshi; Ueno, Nobuhiro; Akutsu, Hiroaki; Ogawa, Naoki; Fujiya, Mikihiro. Sci. Rep. 2021, 11, 1107.

3: Solid-phase Synthesis of Fluorescent Analogues of Park’s Nucleotide, Lipid I and Lipid II. Akira Katsuyama, Fumika Yakushiji, Satoshi Ichikawa Tetrahedron Lett. 2021, 73, 153101.

4: Structure, solubility, and permeability relationships in a diverse middle molecule library Hiroyuki Miyachi, Kayoko Kanamitsu, Mayumi Ishii, Eri Watanabe, Akira Katsuyama, Satoko Otsuguro, Fumika Yakushiji, Mizuki Watanabe, Kouhei Matsui, Yukina Sato, Satoshi Shuto, Takashi Tadokoro, Shunsuke Kita, Takanori Matsumaru, Akira Matsuda, Tomoyasu Hirose, Masato Iwatsuki, Yasuteru Shigeta, Tetsuo Nagano, Hirotatsu Kojima, Satoshi Ichikawa, Toshiaki Sunazuka, Katsumi Maenaka. Bioorganic Med. Chem. Lett. 2021, 37, 127847.

5: Takashina, Kazuki; Katsuyama, Akira; Kaguchi, Rintaro; Yamamoto, Kazuki; Sato, Toyotaka; Takahashi, Satoshi; Horiuchi, Motohiro; Yokota, Shin-ichi; Ichikawa, Satoshi. Solid-Phase Total Synthesis of Plusbacin A3. Org. Lett. 2022, 24, 2253-2257.

6: Okamoto, Kazuhiro; Ishikawa, Aoi; Okawa, Ryotaro; Yamamoto, Kazuki; Sato, Toyotaka; Yokota, Shinichi; Chiba, Kazuhiro; Ichikawa, Satoshi. Design, synthesis and biological evaluation of simplified analogues of MraY inhibitory natural product with rigid scaffold. Bioorg. Med. Chem. 2022, 55, 116556. DOI: 10.1016/j.bmc.2021.116556

Professor Matsunaga

1: Kanki D, Imai K, Ise Y, Okada S, Matsunaga S. Oshimalides A and B, Sesterterpenes of the Manoalide Class from a <i>Luffariella</i> sp. Deep-Sea Marine Sponge: Application of Asymmetric Dihydroxylation in Structure Elucidation. J Nat Prod. 2021 May 28;84(5):1676-1680. doi: 10.1021/acs.jnatprod.1c00320. Epub 2021 May 9. PMID: 33966383.

2: Moosmann P, Taniguchi T, Furihata K, Utsumi H, Ise Y, Morii Y, Yamawaki N, Takatani T, Arakawa O, Okada S, Matsunaga S. Myrindole A, an Antimicrobial Bis- indole from a Marine Sponge <i>Myrmekioderma</i> sp. Org Lett. 2021 May 7;23(9):3477-3480. doi: 10.1021/acs.orglett.1c00922. Epub 2021 Apr 22. PMID: 33885313

3: Chemoselective Cleavage of Si–C(sp3) Bonds in Unactivated Tetraalkylsilanes Using Iodine Tris(trifluoroacetate) Matsuoka, K.; Komami, N.; Kojima, M.; Mita, T.; Suzuki, K.; Maeda, S.; Yoshino, T.; Matsunaga, S. J. Am. Chem. Soc. 2021, 143, 103-108. DOI: 10.1021/jacs.0c11645

4: Metal-Containing Schiff Base/Sulfoxide Ligands for Pd(II)-Catalyzed Asymmetric Allylic C–H Aminations Bunno, Y.; Tsukimawashi, Y.; Kojima, M.; Yoshino, T.; Matsunaga, S. ACS Catal. 2021, 11, 2663-2668. DOI: 10.1021/acscatal.0c05261

5: Silane- and Peroxide-Free Hydrogen Atom Transfer Hydrogenation Using Ascorbic Acid and Cobalt-Photoredox Dual Catalysis Kamei, Y.; Seino, Y.; Yamaguchi, Y.; Yoshino, T.; Maeda, S.; Kojima, M.; Matsunaga, S. Nat. Commun. 2021, 12, 966. DOI: 10.1038/s41467-020-20872-z

6: Development of Pseudo-C2-symmetric Chiral Binaphthyl Monocarboxylic Acids for Enantioselective C(sp3)–H Functionalization Reactions under Rh(III) Catalysis Kato, Y.; Lin, L.; Kojima, M.; Yoshino, T.; Matsunaga, S. ACS Catal. 2021, 11, 4271-4277. DOI: 10.1021/acscatal.1c00765

7: Ru(II)/Chiral Carboxylic Acid-Catalyzed Enantioselective C–H Functionalization of Sulfoximines Huang, L.-T.; Hirata, Y.; Kato, Y.; Lin, L.; Kojima, M.; Yoshino, T.; Matsunaga, S. Synthesis 2021, accepted article. DOI: 10.1055/a-1588-0072

8:Transition-metal-free nucleophilic (211)At-astatination of spirocyclic aryliodonium ylides. Matsuoka K, Obata H, Nagatsu K, Kojima M, Yoshino T, Ogawa M, Matsunaga S. Org Biomol Chem 19(25), 5525-5528 (2021).

Professor Yamaguchi

1: Awazu M, Yamaguchi Y, Nagata M, Miura M, Hida M. Caspase-3 regulates ureteric branching in mice via cell migration. Biochem Biophys Res Commun. 2021 Jun 25;559:28-34. doi: 10.1016/j.bbrc.2021.04.081. Epub 2021 Apr 28. PMID: 33932897.

2: Yoshida A, Kawata D, Shinotsuka N, Yoshida M, Yamaguchi Y, Miura M. Evidence for the involvement of caspases in establishing proper cerebrospinal fluid hydrodynamics. Neurosci Res. 2021 Sep;170:145-153. doi: 10.1016/j.neures.2020.12.006. Epub 2021 Jan 6. PMID: 33417971.

3: Daisuke Anegawa, Yuki Sugiura, Yuta Matsuoka, Masamitsu Sone, Mototada Shichiri, Reo Otsuka, Noriko Ishida, Ken-ichi Yamada, Makoto Suematsu, Masayuki Miura, Yoshifumi Yamaguchi Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol Communications Biology, 2021, 4:796

4: Hisaya Kato, Yoshiro Maezawa, Yasuo Ouchi, Naoya Takayama, Masamitsu Sone, Kanako Sone, Aki Takada-Watanabe, Kyoko Tsujimura, Masaya Koshizaka, Sayaka Nagasawa, Hisako Saitoh, Manami Ohtaka, Mahito Nakanishi, Hidetoshi Tahara, Akira Shimamoto, Atsushi Iwama, Koji Eto, Koutaro Yokote Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome Stem Cell Research, 2021, 53:102360

Professor Nakagawa

Spliceostatin A interaction with SF3B limits U1 snRNP availability and causes premature cleavage and polyadenylation. Yoshimoto R, Chhipi-Shrestha JK, Schneider-Poetsch T, Furuno M, Burroughs AM, Noma S, Suzuki H, Hayashizaki Y,Mayeda A, Nakagawa S, Kaida D, Iwasaki S, Yoshida M. Cell Chem Biol. 2021 Sep 16;28(9):1356-1365.e4. doi: 10.1016/j.chembiol.2021.03.002. Epub 2021 Mar 29.　PMID: 33784500

NEAT1 lncRNA and amyotrophic lateral sclerosis. Nishimoto Y, Nakagawa S, Okano H. Neurochem Int. 2021 Sep 2;150:105175. doi: 10.1016/j.neuint.2021.105175. Online ahead of print. PMID: 344819083

A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, Takeda R, Tsuchiya A, Fukuyama T, Tanaka Y, Yokoyama A, Toya H, Kon A, Nannya Y, Onoguchi-Mizutani R, Nakagawa S, Hirose T, Ogawa S, Akimitsu N, Kitamura T. Cell Rep. 2021 Aug 24;36(8):109576. doi: 10.1016/j.celrep.2021.109576. PMID: 344330544

Ablation of lncRNA Miat attenuates pathological hypertrophy and heart failure. Yang L, Deng J, Ma W, Qiao A, Xu S, Yu Y, Boriboun C, Kang X, Han D, Ernst P, Zhou L, Shi J, Zhang E, Li TS, Qiu H, Nakagawa S, Blackshaw S, Zhang J, Qin G. Theranostics. 2021 Jul 6;11(16):7995-8007. doi: 10.7150/thno.50990. eCollection 2021. PMID: 34335976 Free PMC article.

Paraspeckles are constructed as block copolymer micelles. Yamazaki T, Yamamoto T, Yoshino H, Souquere S, Nakagawa S, Pierron G, Hirose T. EMBO J. 2021 Jun 15;40(12):e107270. doi: 10.15252/embj.2020107270. Epub 2021 Apr 22. PMID: 33885174

ArcRNAs and the formation of nuclear bodies. Nakagawa S, Yamazaki T, Mannen T, Hirose T. Mamm Genome. 2021 Jun 3. doi: 10.1007/s00335-021-09881-5. Online ahead of print. PMID: 34085114 Review.

The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis. Sato M, Kadomatsu T, Miyata K, Warren JS, Tian Z, Zhu S, Horiguchi H, Makaju A, Bakhtina A, Morinaga J, Sugizaki T, Hirashima K, Yoshinobu K, Imasaka M, Araki M, Komohara Y, Wakayama T, Nakagawa S, Franklin S, Node K, Araki K, Oike Y. Nat Commun. 2021 May 5;12(1):2529. doi: 10.1038/s41467-021-22735-7. PMID: 33953175 Free PMC article.

Assistant Professor Sone

1. Masashi Sato, Yasuhiro Shiga, Naoya Takayama, Masamitsu Sone, Kentaro Kosaka, Itsuro Motegi,
   Norichika Mizuki, Kazuhide Inage, Yawara Eguchi, Miyako Narita, Sumihisa Orita, Koji Eto, Seiji Ohtori
   The Effect of Megakaryocytes and Platelets Derived from Human-Induced Pluripotent Stem Cells
   on Bone Formation
   Spine Surgery and Related Research, 2021; 5(3): 196-204