研究業績

1. Jojima K, Kihara A. (2023) Metabolism of sphingadiene and characterization of the sphingadiene-producing enzyme FADS3. Biochim Biophys Acta Mol Cell Biol Lipids, 1868, 159335.
2. Ota A, Morita H, Naganuma T, Miyamoto M, Jojima K, Nojiri K, Matsuda J, Kihara A. (2023) Bifunctional DEGS2 has higher hydroxylase activity toward substrates with very-long-chain fatty acids in the production of phytosphingosine-ceramides. J Biol Chem, 299, 104603.
3. Jojima K, Edagawa M, Sawai M, Ohno Y, Kihara A. (2020)
   Biosynthesis of the anti-lipid-microdomain sphingoid base 4,14-sphingadiene by the ceramide desaturase FADS3. FASEB J, 34, 3318-3335.
4. Swamy M, Murai Y, Ohno Y, Jojima K, Kihara A, Mitsutake S, Igarashi Y, Yu J, Yao M, Suga Y, Anetai M, Monde K. (2018)
   Structure-inspired design of a sphingolipid mimic sphingosine-1-phosphate receptor agonist from a naturally occurring sphingomyelin synthase inhibitor. ChemComm, 54, 12758-12761.