Publications

2025

2024

2023

2022

2021

2020

2019

2018

  • K. Matsuda, T. Tomita, K. Shin-ya, T. Wakimoto, T. Kuzuyama, M. Nishiyama, Discovery of an unprecedented hydrazine-forming machinery in bacteria. J. Am. Chem. Soc. 140, 9083-9086 (2018)
  • T. Kuranaga, K. Matsuda, A. Sano, M. Kobayashi, A. Ninomiya, K. Takada, S. Matsunaga, T. Wakimoto, Total synthesis of a non-ribosomal peptide surugamide B and identification of a new offloading cyclase family. Angew. Chem. Int. Ed., 57, 9447-9451 (2018)
  • Y. Unno, H. Yamamoto, S. Takatsuki, Y. Sato, T. Kuranaga, K. Yazawa, Y. Ono, T. Wakimoto, Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes. Biochim. Biophys. Acta, Lipids Lipid Metab. 1863, 772-782 (2018)
  • T. Kuranaga, A. Fukuba. A. Ninomiya, K. Takada, S. Matsunaga, T. Wakimoto, Diastereoselective total synthesis and structural confirmation of surugamide F
. Chem. Pharm. Bull. 66, 637-641(2018)
  • A. R. Uria, J. Piel, T. Wakimoto, Biosynthetic insights of calyculin- and misakinolide-type compounds in "Candidatus Entotheonella sp.", Methods in Enzymology. 604, 287-330 (2018)
  • A. Takai, M. Eto, K. Hirano, K. Takeya, T. Wakimoto, M. Watanabe, Protein phosphatases 1 and 2A, and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology. J. Physiol. Sci. 68, 1-17 (2018)

2017

  • T. Kuranaga, A. Enomoto. H. Tan, K. Fujita, T. Wakimoto, Total synthesis of theonellapeptolide Id
. Org. Lett. 19, 1366-1369 (2017)
  • T. Wakimoto, Toward dark matter of natural products, Chem. Rec. 17, 1124-1134 (2017)
  • M. Okada, T. Sugita, C. P. Wong, T. Wakimoto, I. Abe, Identification of pyridinium with three indole moieties as an antimicrobial agent. J. Nat. Prod. 80, 1205-1209 (2017)
  • L. Zhang, T. Hashimoto, B. Qin, J. Hashimoto, I. Kozone, T. Kawahara, M. Okada, T. Awakawa, T. Ito, Y. Asakawa, M. Ueki, S. Takahashi, H. Osada, T. Wakimoto, H. Ikeda, K. Shin-ya, I. Abe, Characterization of giant modular PKSs provides insight into genetic mechanism for structural diversification of aminopolyol polyketides
. Angew. Chem. Int. Ed., 56, 1740-1745 (2017)
  • 倉永健史:セリンライゲーションを鍵としたteixobactinの全合成 ファルマシア 53, 586 (2017)
  • 倉永健史:化学合成を駆使した稀少天然物化学研究 生薬・薬用植物研究の最新動向 (シーエムシー出版) p.125-132 (2017)

2016

  • T. Wakimoto, Y. Egami, I. Abe, Calyculin: Nature’s way of making the sponge-derived cytotoxin. Nat. Prod. Rep., 33, 751-760 (2016)
  • Y. Nakashima, Y. Egami, M. Kimura, T. Wakimoto, I. Abe, Metagenomic analysis of the sponge Discodermia reveals the production of the cyanobacterial natural product kasumigamide by 'Entotheonella'. PLoS ONE, 11, e0164468 (2016)
  • K. C. Tan, T. Wakimoto, I. Abe, Sulfoureido lipopeptides from the marine sponge Discodermia kiiensis. J. Nat. Prod., 79, 2418-2422 (2016)
  • A. Ninomiya, Y. Katsuyama, T. Kuranaga, M. Miyazaki, Y. Nogi, S. Okada, T. Wakimoto, Y. Ohnishi, S. Matsunaga, K. Takada, Biosynthetic gene cluster for surugamide A encompassses an unrelated decapeptide, surugamide F. ChemBioChem, 17, 1709-1712 (2016)
  • L. Zhang, S. Hoshino, T. Awakawa, T. Wakimoto, I. Abe, Structural diversification of lyngbyatoxin A by host-dependent heterologous expression of the tleABC biosynthetic gene cluster. ChemBioChem, 17, 1407-1411 (2016)
  • B. Qin, Y. Matsuda, T. Mori, M. Okada, Z. Quan, T. Mitsuhashi, T. Wakimoto, I. Abe, An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion to a sesterterpene synthase by domain swapping
. Angew. Chem. Int. Ed., 55, 1658-1661 (2016)
  • M. Yamashita, K. Shimizu, Y. Koizumi, T. Wakimoto, Y. Hamashima, T. Asakawa, M. Inai, T. Kan, Concise synthesis of anserine: Efficient solvent tuning in asymmetric hydrogenation reaction. Synlett, 27, 2734-2736 (2016)
  • T. Asakawa, Y. Kawabe, A. Yoshida, Y. Aihara, T. Manabe, Y. Hirose, A. Sakurada, M. Inai, Y. Harashima, T. Furuta, T. Wakimoto, T. Kan, Syntheses of methylated catechins and theaflavins using 2-nitrobezenesulfonyl group to protect and deactivate phenol. J. Antibiot. 69, 299-312 (2016)
  • T. Asakawa, Y. Yoshida, Y. Hirooka, T. Suzuki, K. Itoh, K. Shimizu, N. Oku, T. Furuta, T. Wakimoto, M. Inai, T. Kan, Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate. Heterocycles, 93, 218-242 (2016)
  • 江上蓉子、脇本敏幸、阿部郁朗:海綿共生微生物による生物活性物質の生産 バイオインダストリー 33, 11-17 (2016)
  • 脇本敏幸:カリクリンの生合成 天然物の化学 -魅力と展望- (上村大輔 編) 科学のとびら60 (東京化学同人) p.61-66 (2016)

2015

  • Y. Matsuda, T. Iwabuchi, T. Wakimoto, T. Awakawa, I. Abe, Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase. J. Am. Chem. Soc., 137, 3393-3401 (2015)
  • T. Mori, S. Hoshino, S. Sahashi, T. Wakimoto, T. Matsui, H. Morita, I. Abe, Structural basis for the beta-carboline alkaloids production by the microbial homodimeric enzyme McbB. Chem. Biol., 22, 898-906 (2015)
  • S. Hoshino, T. Wakimoto, H. Onaka, I. Abe, Chojalactones A-C, cytotoxic butanolides isolated from Streptomyces sp. cultivated with mycolic acid containing bacterium. Org. Lett., 17, 1501-1504 (2015)
  • S. Hoshino, M. Okada, T. Wakimoto, H. Zhang, F. Hayashi, H. Onaka, I. Abe, Niizalactams A-C, multicyclic macrolactams isolated from combined culture of Streptomyces with mycolic acid-containing bacterium. J. Nat. Prod., 78, 3011-3017 (2015)
  • T. Asakawa, A. Yoshida, Y. Hirooka, T. Suzuki, K. Itoh, K. Shimizu, N. Oku, T. Furuta, T. Wakimoto, M. Inai, T. Kan, Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate. Heterocycles, 93, 218-242 (2015)
  • Y. Takeshige, Y. Egami, T. Wakimoto, I. Abe, Production of indole antibiotics induced by exogenous gene derived from sponge metagenome. Mol. BioSyst., 11, 1290-1294 (2015)
  • S. Hoshino, T. Wakimoto, H. Zhang, F. Hayashi, M. Okada, I. Abe, Dietziamides, novel tetramic acid dimers from Dietzia timorensis MZ-3 with antioxidative activity. Bioorg. Med. Chem. Lett., 25, 3953-3955 (2015)
  • S. Hoshino, L. Zhang, T. Awakawa, T. Wakimoto, H. Onaka, I. Abe, Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823. J. Antibiot., 68, 342-344 (2015)
  • T. Wakimoto, K. C. Tan, H. Tajima, I. Abe, Cytotoxic cyclic peptides from the marine sponges. Anticancer Drug from Marine Origin, Springer, Chapter 6, pp. 113-144 (2015)
  • 江上蓉子、脇本敏幸、阿部郁朗:海綿動物の化学防御を担う共生菌 細胞工学 34, 412-416 (2015)
  • 脇本敏幸、江上蓉子、阿部郁朗:海綿-共生微生物系の化学防御機構 化学と生物 53, 497-499 (2015)
  • 脇本敏幸、阿部郁朗:カイメンー共生バクテリア系の化学防御機構 バイオサイエンスとインダストリー 73, 49-51 (2015)