K. Fujita, R. Ichihara, M. Kobayashi, K. Matsuda, T. Wakimoto, Diol as a new pantetheine surrogate for chemoenzymatic synthesis of cyclic peptides via non-ribosomal peptide cyclases. Methods Mol. Biol., in press (2024)
A. Uria, J. Piel, T. Wakimoto, Biosynthesis of non-ribosomal peptides in uncultivated bacterial symbionts of marine sponges. Marine Sponge Biotechnology and Bioproducts, in press (2022)
K. Matsuda, T. Tomita, K. Shin-ya, T. Wakimoto, T. Kuzuyama, M. Nishiyama, Discovery of an unprecedented hydrazine-forming machinery in bacteria. J. Am. Chem. Soc. 140, 9083-9086 (2018)
T. Kuranaga, K. Matsuda, A. Sano, M. Kobayashi, A. Ninomiya, K. Takada, S. Matsunaga, T. Wakimoto, Total synthesis of a non-ribosomal peptide surugamide B and identification of a new offloading cyclase family. Angew. Chem. Int. Ed., 57, 9447-9451 (2018)
Y. Unno, H. Yamamoto, S. Takatsuki, Y. Sato, T. Kuranaga, K. Yazawa, Y. Ono, T. Wakimoto, Palmitoyl lactic acid induces adipogenesis and a brown fat-like phenotype in 3T3-L1 preadipocytes. Biochim. Biophys. Acta, Lipids Lipid Metab. 1863, 772-782 (2018)
T. Kuranaga, A. Fukuba. A. Ninomiya, K. Takada, S. Matsunaga, T. Wakimoto, Diastereoselective total synthesis and structural confirmation of surugamide F . Chem. Pharm. Bull. 66, 637-641(2018)
A. R. Uria, J. Piel, T. Wakimoto, Biosynthetic insights of calyculin- and misakinolide-type compounds in "Candidatus Entotheonella sp.", Methods in Enzymology. 604, 287-330 (2018)
A. Takai, M. Eto, K. Hirano, K. Takeya, T. Wakimoto, M. Watanabe, Protein phosphatases 1 and 2A, and their naturally occurring inhibitors: current topics in smooth muscle physiology and chemical biology. J. Physiol. Sci. 68, 1-17 (2018)
2017
T. Kuranaga, A. Enomoto. H. Tan, K. Fujita, T. Wakimoto, Total synthesis of theonellapeptolide Id . Org. Lett. 19, 1366-1369 (2017)
T. Wakimoto, Toward dark matter of natural products, Chem. Rec. 17, 1124-1134 (2017)
M. Okada, T. Sugita, C. P. Wong, T. Wakimoto, I. Abe, Identification of pyridinium with three indole moieties as an antimicrobial agent. J. Nat. Prod.80, 1205-1209 (2017)
L. Zhang, T. Hashimoto, B. Qin, J. Hashimoto, I. Kozone, T. Kawahara, M. Okada, T. Awakawa, T. Ito, Y. Asakawa, M. Ueki, S. Takahashi, H. Osada, T. Wakimoto, H. Ikeda, K. Shin-ya, I. Abe, Characterization of giant modular PKSs provides insight into genetic mechanism for structural diversification of aminopolyol polyketides . Angew. Chem. Int. Ed.,56, 1740-1745 (2017)
T. Wakimoto, Y. Egami, I. Abe, Calyculin: Nature’s way of making the sponge-derived cytotoxin. Nat. Prod. Rep., 33, 751-760 (2016)
Y. Nakashima, Y. Egami, M. Kimura, T. Wakimoto, I. Abe, Metagenomic analysis of the sponge Discodermia reveals the production of the cyanobacterial natural product kasumigamide by 'Entotheonella'. PLoS ONE, 11, e0164468 (2016)
K. C. Tan, T. Wakimoto, I. Abe, Sulfoureido lipopeptides from the marine sponge Discodermia kiiensis. J. Nat. Prod., 79, 2418-2422 (2016)
A. Ninomiya, Y. Katsuyama, T. Kuranaga, M. Miyazaki, Y. Nogi, S. Okada, T. Wakimoto, Y. Ohnishi, S. Matsunaga, K. Takada, Biosynthetic gene cluster for surugamide A encompassses an unrelated decapeptide, surugamide F. ChemBioChem, 17, 1709-1712 (2016)
L. Zhang, S. Hoshino, T. Awakawa, T. Wakimoto, I. Abe, Structural diversification of lyngbyatoxin A by host-dependent heterologous expression of the tleABC biosynthetic gene cluster. ChemBioChem, 17, 1407-1411 (2016)
B. Qin, Y. Matsuda, T. Mori, M. Okada, Z. Quan, T. Mitsuhashi, T. Wakimoto, I. Abe, An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion to a sesterterpene synthase by domain swapping . Angew. Chem. Int. Ed.,55, 1658-1661 (2016)
M. Yamashita, K. Shimizu, Y. Koizumi, T. Wakimoto, Y. Hamashima, T. Asakawa, M. Inai, T. Kan, Concise synthesis of anserine: Efficient solvent tuning in asymmetric hydrogenation reaction. Synlett, 27, 2734-2736 (2016)
T. Asakawa, Y. Kawabe, A. Yoshida, Y. Aihara, T. Manabe, Y. Hirose, A. Sakurada, M. Inai, Y. Harashima, T. Furuta, T. Wakimoto, T. Kan, Syntheses of methylated catechins and theaflavins using 2-nitrobezenesulfonyl group to protect and deactivate phenol. J. Antibiot. 69, 299-312 (2016)
T. Asakawa, Y. Yoshida, Y. Hirooka, T. Suzuki, K. Itoh, K. Shimizu, N. Oku, T. Furuta, T. Wakimoto, M. Inai, T. Kan, Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate. Heterocycles, 93, 218-242 (2016)
Y. Matsuda, T. Iwabuchi, T. Wakimoto, T. Awakawa, I. Abe, Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase. J. Am. Chem. Soc.,137, 3393-3401 (2015)
T. Mori, S. Hoshino, S. Sahashi, T. Wakimoto, T. Matsui, H. Morita, I. Abe, Structural basis for the beta-carboline alkaloids production by the microbial homodimeric enzyme McbB. Chem. Biol., 22, 898-906 (2015)
S. Hoshino, T. Wakimoto, H. Onaka, I. Abe, Chojalactones A-C, cytotoxic butanolides isolated from Streptomyces sp. cultivated with mycolic acid containing bacterium. Org. Lett.,17, 1501-1504 (2015)
S. Hoshino, M. Okada, T. Wakimoto, H. Zhang, F. Hayashi, H. Onaka, I. Abe, Niizalactams A-C, multicyclic macrolactams isolated from combined culture of Streptomyces with mycolic acid-containing bacterium. J. Nat. Prod., 78, 3011-3017 (2015)
T. Asakawa, A. Yoshida, Y. Hirooka, T. Suzuki, K. Itoh, K. Shimizu, N. Oku, T. Furuta, T. Wakimoto, M. Inai, T. Kan, Synthesis of chemical-biology tools enabling in vivo imaging and analysis of epigallocatechin gallate. Heterocycles, 93, 218-242 (2015)
Y. Takeshige, Y. Egami, T. Wakimoto, I. Abe, Production of indole antibiotics induced by exogenous gene derived from sponge metagenome. Mol. BioSyst.,11, 1290-1294 (2015)
S. Hoshino, T. Wakimoto, H. Zhang, F. Hayashi, M. Okada, I. Abe, Dietziamides, novel tetramic acid dimers from Dietzia timorensis MZ-3 with antioxidative activity. Bioorg. Med. Chem. Lett.,25, 3953-3955 (2015)
S. Hoshino, L. Zhang, T. Awakawa, T. Wakimoto, H. Onaka, I. Abe, Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823. J. Antibiot., 68, 342-344 (2015)
T. Wakimoto, K. C. Tan, H. Tajima, I. Abe, Cytotoxic cyclic peptides from the marine sponges. Anticancer Drug from Marine Origin, Springer, Chapter 6, pp. 113-144 (2015)