研究業績

原著論文・総説

1. Kono Y, Iwasaki A, Fujita T. Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer. Pharmazie 2018, 73 (1), 3-8.
2. Kono Y, Nakai T, Taguchi H, Fuhita T. Development of magnetic anionic liposome/atelocollagen complexes for efficient magnetic drug targeting. Drug Delv 2017, 24 (1), 1740-1749.
3. Kono Y, Jinzai H, Kotera Y, Fujita T. Influence of physicochemical properties and PEG modification of magnetic liposomes on their interaction with intestinal epithelial Caco-2 cells. Biol Pharm Bull 2017, 40 (12), 2166-2174.
4. Kono Y, Miyoshi S, Fujita T. Dextran sodium sulfate alters cytokine production in macrophages in vitro. Pharmazie 2016, 71 (11), 619-624.
5. Kono Y, Iwasaki A, Matsuoka K, Fujita T. Effect of mechanical agitation on cationic liposome transport across an unstirred water layer in Caco-2 cells. Biol Pharm Bull 2016, 39 (8), 1293-1299.
6. Konishi S, Fujita T, Hattori K, Kono Y, Matsushita Y. An openable artificial intestinal tract system for the in vitro evaluation of medicines. Microsys Nanoeng 2015, 1, 15015.
7. Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. Int J Pharm 2014, 475 (1-2), 401-407.
8. Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. Cancer Sci 2014, 105 (8), 1049-1055.
9. Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. J Drug Target 2014, 22 (8), 732-738.
10. Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. J Drug Target 2014, 22 (5), 439-449.
11. Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M. In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. Biol Pharm Bull 2014, 37 (1), 127-144.
12. Araki T, Kono Y, Ogawara K, Watanabe T, Ono T, Kimura T, Higaki K. Formulation and evaluation of paclitaxel-loaded polymeric nanoparticles composed of polyethylene glycol and polylactic acid block copolymer. Biol Pharm Bull 2012, 35 (8), 1306-1313.
13. Un K, Kono Y, Yoshida M, Yamashita F, Kawakami S, Hashida M. Enhancement of gene expression by transcriptional activation using doxorubicin-loaded liposome/pDNA complexes. Pharmazie 2012, 67 (5), 400-405.
14. Yoshizawa Y, Kono Y, Ogawara K, Kimura T, Higaki K. PEG liposomalization of paclitaxel improved its in vivo disposition and anti-tumor efficacy. Int J Pharm 2011, 412 (1-2), 132-141.

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