北海道大学大学院 薬学研究院 創薬科学研究教育センター 有機合成医薬学部門

研究業績

発表論文 2010年

  1. Incorporation of 2´-Deoxy-2´-Isonucleoside 5´-Triphosphates (iNTPs) into DNA by A- and B-Family DNA Polymerases with Different Recognition Mechanisms.

    Ogino, T.; Sato, K.; Matsuda, A.

    ChemBioChem 2010, 11, 2597-2605. DOI: 10.1002/cbic.201000449

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  2. Selective Detection of 5-Formyl-2´-deoxyuridine, an Oxidative Lesion of Thymidine, in DNA by a Fluorogenic Reagent.

    Hirose, W.; Sato, K.; Matsuda, A.

    Angew. Chem., Int. Ed. 2010, 49, 8392-8394. DOI: 10.1002/anie.201004087

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  3. Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as check point 1 kinase inhibitors.

    Sako, Y.; Ichikawa, S.; Osada, A.; Matsuda, A.

    Bioorg. Med. Chem. 2010, 18, 7878-7889. DOI: 10.1016/j.bmc.2010.09.042

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  4. Synthesis and Biological Evaluation of Muraymycin Analogues Active against Anti-Drug-Resistant Bacteria.

    Tanino, T.; Ichikawa, S.; Al-Dabbagh, B.; Boushss, A.; Oyama, H.; Matsuda, A.

    ACS Med. Chem. Lett. 2010, 1, 258-262. DOI: 10.1021/ml100057z

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  5. Efficient synthesis of Hsp90 inhibitor dimers as potential antitumor agents.

    Sekiguchi, H.; Muranaka, K.; Osada, A.; Ichikawa, S.; Matsuda, A.

    Bioorg. Med. Chem. 2010, 18, 5732-5737. DOI: 10.1016/j.bmc.2010.05.075

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  6. Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria.

    Ii, K.; Ichikawa, S.; Al-Dabbagh, B.; Boushss, A.; Matsuda, A.

    J. Med. Chem. 2010, 53, 3793-3813. DOI: 10.1021/jm100243n

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  7. A new arylsulfate sulfotransferase involved in liponucleoside antibiotic biosynthesis in streptomycetes.

    Kaysser, L.; Eitel, K.; Tanino, T.; Sienberg, S.; Matsuda, A.; Ichikawa, S.; Gust, B.

    J. Biol. Chem. 2010, 285, 12684-12694. DOI: 10.1074/jbc.M109.094490

  8. 新たな切り口で結核菌と戦う!

    市川 聡、松田 彰

    化学, 2010, 65 (2), 30-34.

  9. Total Synthesis of (–)-Muraymycin D2 and Its Epimer.

    Tanino, T.; Ichikawa, S.; Shiro, M.; Matsuda A.

    J. Org. Chem. 2010, 75, 1366-1377. DOI: 10.1021/jo9027193

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