Publications

研究業績

2009

Ohno Y, Ito A, Ogata R, Hiraga Y, Igarashi Y, Kihara A (2009) Palmitoylation of the sphingosine 1-phosphate receptor S1P₁ is involved in its signaling functions and internalization. Genes Cells, 14, 911-923.
Balan L, Foltyn VN, Zehl M, Dumin E, Dikopoltsev E, Knoh D, Ohno Y, Kihara A, Jensen ON, Radzishevsky IS, Wolosker H (2009) Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane. Proc Natl Acad Sci USA,106, 7589-7594.
E S, Lai Y, Tsukahara R, Chen C, Fujiwara Y, Yue J, Yu J, Guo H, Kihara A, Tigyi G, Lin F (2009) The LPA₂ receptor-mediated supramolecular complex formation regulates its anti-apoptotic effect. J Biol Chem, 284, 14558-14571.
Mizutani Y, Mitsutake S, Tsuji K, Kihara A, Igarashi Y (2009) Ceramide biosynthesis in keratinocyte and its role in skin function. Biochimie, 91, 784-790. Review
木原章雄 (2009)「北から南から」生化学, 81, 626. 生化学研究室の紹介

学会発表

須藤将太, 山中雅夫, 大野祐介, 佐々貴之, 木原章雄; Regulation of very long-chain fatty acid elongation by ceramide synthase. 第32回日本分子生物学会年会, 横浜, 2009. 12. 11.
小西宏侑, 奥田彩佳, 木原章雄; Biochemical analysis of HACD1 K64Q mutant found in arrhythmogenic right ventricular dysplasia patients. 第32回日本分子生物学会年会, 横浜, 2009. 12. 11.
小原圭介, 山本林, 大隅良典, 木原章雄; Analysis of the sensor proteins in the Rim101 pathway detecting lipid asymmetry. 第32回日本分子生物学会年会, 横浜, 2009. 12. 9.
木原章雄; Metabolism and functions of sphingosine 1-phosphate and FTY720. 第31回生体膜と薬物の相互作用シンポジウム, 大阪, 2009. 11. 30.
須藤将太, 山中雅夫, 大野祐介, 佐々貴之, 木原章雄; セラミド合成による極長鎖脂肪酸伸長の調節機構. 第2回セラミド研究会学術集会, 札幌, 2009. 11. 6.
木原章雄, 小原圭介; Rim101経路による脂質非対称感知システムの分子機構. 第82回日本生化学会大会, 神戸, 2009. 10. 24.
Kihara A, Igarashi Y; Synthesis of very long-chain fatty acid and its relationship to sphingolipid metabolism. 50th International Conference on the Bioscience of Lipids, Regensburg, Germany, 2009. 9. 4.
Ohno Y, Igarashi Y, Kihara A; ELOVL7 is a fatty acid elongase exhibiting high activities toward C18-CoAs. 50th International Conference on the Bioscience of Lipids, Regensburg, Germany, 2009. 9. 2.
山形麻旗, 小原圭介, 木原章雄; 酵母を用いたオートファジー誘導におけるスフィンゴ脂質の機能解析. 第51回日本脂質生化学会, 名古屋, 2009. 7. 30.
大野祐介, 山形麻旗, 五十嵐靖之, 木原章雄; 極長鎖脂肪酸伸長酵素ELOVL7はC18-CoAに高い酵素活性を示しC24スフィンゴ脂質合成に関わる. 第51回日本脂質生化学会, 名古屋, 2009. 7. 30.
木原章雄; 脂肪酸の多彩な代謝と機能. 日本生化学会北海道支部第46回例会, 旭川, 2009. 7. 17.
Obara K, Ikeda M, Igarashi Y, Kihara A; Analysis of the putative sensor proteins in the RIM101 pathway detecting lipid asymmetry. 4th International conference on phospholipase A2 and lipid mediators, Tokyo, 2009. 5. 27.
Kihara A; Synthesis of very long-chain fatty acid and its relationship to sphingolipid metabolism and transport. 4th International conference on phospholipase A2 and lipid mediators, Tokyo, 2009. 5. 27.

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