Chemical Library

Previous chemical library screening research results

Institution  Used Library Publication/Patent
The University of Tokyo HOKUDAI Proprietary & Middle-molecules Library Miyachi, Hiroyuki, et al. "Structure, solubility, and permeability relationships in a diverse middle molecule library." Bioorganic & Medicinal Chemistry Letters 37 (2021): 127847.
Hokkaido University Approved Drug Library Patent Application Publication 2021-134181(P2021-134181A) Anti-Hepatitis B virus agent
Hokkaido University HOKUDAI Proprietary Library Maeda, Naoyoshi, et al. "Antitumor Effect of Sugar-Modified Cytosine Nucleosides on Growth of Adult T-Cell Leukemia Cells in Mice." Vaccines 8.4 (2020): 658.
Hokkaido University Todai-DDI validated library Shiraishi, Takaya, et al. "Novel Notch signaling inhibitor NSI‑1 suppresses nuclear translocation of the Notch intracellular domain." International Journal of Molecular Medicine 44.4 (2019): 1574-1584.
Hokkaido University Approved Drug Library  Sarwono, Albertus Eka Yudistira, et al. "Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening." Journal of enzyme inhibition and medicinal chemistry 34.1 (2019): 171-178.
Sapporo Medical University Approved Drug Library  Patent Application Publication 2019-71853(P2019-71853A) Antibiotic screening method
Hokkaido University Approved Drug Library  Kakuguchi, Wataru, et al. "Suramin, screened from an approved drug library, inhibits HuR functions and attenuates malignant phenotype of oral cancer cells." Cancer medicine 7.12 (2018): 6269-6280.
Hokkaido University HOKUDAI Proprietary Library Anindita, Paulina D., et al. "Ribavirin-related compounds exert in vitro inhibitory effects toward rabies virus." Antiviral research 154 (2018): 1-9.
Hokkaido University HOKUDAI Proprietary Library Patent Application Publication 2018-87173(P2018-87173A) Malignant brain tumour therapeutics
Obihiro university of agriculture and veterinary medicine Todai-DDI validated library Murata, Yuho, et al. "Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites." PLoS One 12.6 (2017): e0178203.
Hokkaido University HOKUDAI Proprietary Library Tsukamoto, Yoshihiro, et al. "Chemical screening identifies EUrd as a novel inhibitor against temozolomide-resistant glioblastoma-initiating cells." Stem Cells 34.8 (2016): 2016-2025.