・
Pd(II)-Catalyzed Alkylation of Tertiary Carbon via Directing Group-Mediated C(sp3)-H Activation: Synthesis of Chiral 1,1,2-Trialkylsubstituted Cyclopropane. N. Hoshiya, K. Takenaka, S. Shuto, J. Uenishi, Organic Letters, 2016, 18, 48-51.
・
Novel Characteristics of Guanosine 5’-monophosphate 1 Reductase in Pathogenic2 Protozoa Trypanosoma brucei Distinct from Host Animal. T. Bessho, T. Okada, C. Kimura, T. Shinohara, A. Tomiyama, A. Imamura, M. Kuwamura, K. Nishimura, K. Fujimori, .S. Shuto, O. Ishibashi, B. K. Kubata, T. Inui, PLOS Neglected Tropical Diseases, 2016,10, e0004339. doi:10.1371/jpirma;.pntd.0004339.
・
Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction. H. Fukuda, S. Ito, K. Watari, C. Mogi, M. Arisawa, F. Okajima, H. Kurose, S. Shuto, ACS Medicinal Chemistry Letters,2016, 7, 493-497. doi: 10.1021/acsmedchemlett.6b00014
・
Identification of Adenine and Benzimidazole Nucleosides as Potent Human Concentrative Nucleoside Transporter 2 Inhibitors: Potential Treatment for Hyperuricemia and Gout. K. Tatani, M. Hiratochi, N. Kikuchi, Y. Kuramochi, S. Watanabe, Y. Yamauchi, M. Isaji, S, Shuto Journal of Medicinal Chemistry , 2016, 59, 3719-3731. doi: 10.1021/acs.jmedchem.5b01884.
・
Non-metathesis Heterocycle Formation by Ruthenium-Catalyzed Intramolecular [2+2] Cycloaddition of Allenamide-enes to Azabicyclo[3.1.1]heptanes. T. Nada, Y. Yoneshige, Y. Ii, T. Matsumoto, H. Fujioka, S. Shuto, M. Arisawa, ACS catalysis, 2016, 6, 3168-3171. doi: 10.1021/acscatal.6b00628.
・
Highly Sensitive Measurement of Inositol 1,4,5-Trisphosphate Using a Novel Fluorescent Ligand and Ligand-Binding Domain Combination. T. Oura, K. Murata, T. Morita, A. Nezu, M. Arisawa, S. Shuto, A. Tanimura, ChemBioChem, 2016, 17, 1509-1512. doi: 10.1002/cbic.201600096.
・
Self-assembled Multi-layer Stabilized Nickel Nanoparticle Catalyst for Ligand-free Cross-coupling Reactions: in situ Metal Nanoparticle and Nanospace Simultaneous Organization. N. Hoshiya, K. Fujiki, T. Taniguchi, T. Honma, Y. Tamenori, M. Xiao, N. Saito, M. Yokoyama, A. Ishii, H. Fujioka, S. Shuto, Y. Sato, M. Arisawa, Advanced Synthesis & Catalysis, 2016, 15, 2449-2459. doi: 10.1002/adsc.201600024.
・
Design,Synthesis, and Identification of 4”α-Azidoethyl-Cyclic ADP-Carbocyclic-Ribose as a Highly Potent Analogue of Cyclic ADP-Ribose, a Ca2+-mobilizing Second Messenger. T. Sato, M. Watanabe, T. Tsuzuki, S. Takano, T. Murayama, T. Sakurai, T. Kameda, H. Fukuda, M. Arisawa, S. Shuto, Journal of Medicinal Chemistry, 2016, 59, 7282-7286.
・
Development of a Sulfur-modified Glass-supported Pd Nanoparticle Catalyst for the Suzuki-Miyaura Coupling. M. Xiao, N. Hoshiya, K. Fujiki, T. Honma, Y. Tamenori, S. Shuto, H. Fujioka, M. Arisawa, Chemical and Pharmaceutical Bulletin, 2016, 54, 1154-1161.
・
Design and synthesis of cyclopropane congeners of reslvin E2, an endogenous proresolving lipid mediator, as its stable equivalents. H. Fukuda, R. Muromoto, Y. Takakura, K. Ishimura, R. Kanada, D. Fushihara, M. Tanabe, K. Matsubara, T. Hirao, K. Hirashima, H. Abe, M. Arisawa, S. Shuto,Organic Letters, 2016, 18, 6224-6227.
その他の総説等
All Rights Reserved Laboratory of Organic Chemistry for Drug Development
