2014年

1. ・ Automatic Pseudorotaxane Formation Targeting on Nucleic Acids Using a Pair of Reactive Oligodeox-ynucleotides. K. Onizuka, F. Nagatsugi, Y. Ito, H. Abe. Journal of the American Chemical Society, 2014, 136, 7201-7204.
   


2. ・ Triphenylphoshinecarbomide: an effective reagent for the reduction of azides and its application to nucleic acid detection. H. Saneyoshi, T. Ochikubo, T. Mashimo, K. Hatano, Y. Ito, H. Abe. Organic Letters, 2014, 16, 30-33.
   


3. ・ Intracellular buildup reaction of active siRNA species from short RNA fragments. H. Maruyama, Y. Nakashima, S. Shuto, A. Matsuda, Y. Ito, H. Abe. Chemical Communications, 2014, 50, 1284-1287.
   


4. ・ Transmembrane molecular transport through nanopores formed by protein nanotubes. B. G. Nair, Y. Nakano, Y. Ito, H. Abe. Chemical Communications, 2014, 50, 602-604.
   


5. ・ Rational hopping of a peptidic scaffold into non-peptidic scaffolds: structurally novel potant proteasome inhibitors derived from a natural product, belactosin A. S. Kawamura, Y. Unno, T. Hirokawa, A. Asai, M. Arisawa, S. Shuto. Chemical Communications, 2014, 50, 2445-2447.
   


6. ・ Structurally novel highly potent proteasome inhibitors created by the dtructure-nased hybridization of non-peptidic belactosin derivatives and peptide boronates. S. Kawamura, Y. Unno, A. Asai, M. Arisawa, S. Shoto. Journal of Medicinal Chemistry, 2014, 57, 2726-2735.
   


7. ・ Ligand-free Suzuki-Miyaura Coupling with Sulfur-modified Gold-supported Palladium in the Synthesis of a Conformationally-Restricted Cyclopropane Compound Library with Three-Dimensional Diversity. M. Arisawa, T. Sato, N. Hoshiya, M. Al-Amin, Y. Kogami, S. Shuto. ACS Comb. Sci., 2014, 16, 215-220.
   


8. ・ Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor. T. Kobayashi, A. Suemasa, A. Igawa, S. Ide, H. Fukuda, H. Abe, M. Arisawa, M. Minami, S. Shuto. ACS Medicinal Chemistry Letters, 2014, 5, 889-893.
   


9. ・ Palladium-Nanoparticle-Catalyzed 1,7-Palladium Migration Involving C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of N1-Arylbenzotriazoles and an Evaluation of Their Inhibitory Activity toward Indoleamine 2,3-Dioxygenase. K. Takagi, M. Al-Amin, N. Hoshiya, J. Wouters, H. Sugimoto, Y. Shiro, H. Fukuda, S. Shuto, M. Arisawa. Journal of Organic Chemistry., 2014, 79, 6366-6371.
   


10. ・ Palladium Nanoparticle-Catalyzed Direct Ethynylation of Aliphatic Carboxylic Acid Derivatives via C(sp3) H Bond Functionalization. M. Al-Amin, M. Arisawa, S. Shuto, Y. Ano, M. Tobisu, N. Chatani. Advanced Synthesis & Catalysis, 2014, 356, 1631-1637.
    


11. ・ Development of a New Class of Proteasome Inhibitors with an Epoxyketone Warhead: Rational Hybridization of Non-Peptidic Belactosin Derivatives and Peptide Epoxyketones. S. Kawamura, Y. Unno, A. Asai, M. Arisawa, S. Shuto. Bioorganic & Medicinal Chemistry, 2014, 22, 3091-3095.
    


12. ・ Synthesis of 3',4'-difluoro-3'-deoxyribonucleosides and its evaluation of the biological activities: Discovery of a novel type of anti-HCV agent 3',4'-difluorocordycepin. H. Shimada, K. Haraguchi, K. Hotta, T. Miyaike, Y. Kitagawa, H. Tanaka, R. Kaneda, H. Abe, S. Shuto, K. Mori, Y. Ueda, N. Kato, R. Snoeck, G. Andrei, J. Balzarini. Bioorganic & Medicianl Chemistry, 2014, 22, 6174-6182.
    


13. ・ Formation of self-assembled multi-layer stable　palladium nanoparticles for ligand-free coupling　reactions. M. Arisawa, M. Al-Amin, T. Honma, Y. Tamenori, S. Arai, N. Hoshiya, T. Sato, M. Yokoyama, A. Ishii, M. Takeguchi, T. Miyazaki, M. Takeuchi, T. Maruko, S. Shuto. RSC Advances, 2014, 5 676-683.
    


14. ・ Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose. T. Tsuzuki, S. Takano, N. Sakaguchi, T. Kudoh, T. Murayama, T. Sakurai, M. Hashii, H. Higashida, K. Weber, A. H. Guse, T. Kameda, T. Hirokawa, Y. Kumaki, M. Arisawa, B. V. L. Potter, S. Shuto. Messenger, 2014, 3, 35-51.
    

その他の総説等

1. ・ 柴田綾，鵜澤尊規，伊藤嘉浩，周東智，阿部洋, 「非酵素的に高効率シグナル増幅を可能とする新規RNA検出法を開発」、化学と生物、2014, 52, 771-776.
   


2. ・ 伊藤美香、周東智、伊藤嘉浩、阿部洋、「グルタチオントランスフェラーゼを標的とした分子プローブの開発」有機合成化学協会誌、2014, 72, 822-831.