2015年

1. ・ Lipo-oxytocin-1, A Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-lasting Effects on Anxiety-related Behavior and Social Avoidance in CD157 Knockout Mice. A. Mizuno, S. M. Cherepanov, Y. Kikuchi, A. Fakhrul, S. Akther, K. Deguchi, T. Yoshihara, K. Ishihara, S. Shuto , H. Higashida. Brain Sciences, 2015, 5, 3-13.
   


2. ・ Determination of ω-6 and ω-3 PUFA metabolites in human urine samples using UPLC/MS/MS. A. Sasaki, H. Fukuda, N. Shiida, N. Tanaka, A. Furugen, J. Ogura, S. Shuto, N. Mano, H. Yamaguchi. Analytical and Bioanalytical Chemistry, 2015, 407, 1625-1639.
   


3. ・ Identification of 8-Aminoadenosine Derivatives as a New Class of Human Concentrative Nucleoside Transporter 2 Inhibitors. K. Tatani, M. Hiratochi, Y. Nonaka, M. Isaji, S. Shuto. ACS Medicinal Chemistry Letters, 2015, 6, 244-248.
   


4. ・ Nickel-Catalyzed Suzuki?Miyaura Coupling of a Tertiary Iodocyclopropane with Wide Boronic Acid Substrate Scope: Coupling Reaction Outcome Depends on Radical Species Stability. Yotsuji, N. Hoshiya, T. Kobayashi, H. Fukuda, H. Abe, M. Arisawa, S. Shuto. Advanced Synthesis & Catalysis, 2015, 357, 1022-1028.
   


5. ・ Double carbonylation of aryl iodides with amines under an atmospheric pressure of carbon monoxide using sulfur-modified Au-supported palladium. N. Saito,T. Taniguchi,N. Hoshiya, S. Shuto, M. Arisawa, Y. Sato. Green Chemistry, 2015, 17, 2358-2361.
   


6. ・ Characterization of imidazopyridine compounds as negative allosteric modulators of proton-sensing GPR4 in extracellular acidification-induced responses. A. Tobo, M. Tobo, T. Nakakura, M. Ebara, H. Tomura, C. Mogi, D.-S. Im, N. Murata, A. Kuwabara, S. Ito, H. Fukuda, M. Arisawa, S. Shuto, M. Nakaya, H. Kurose, K. Sato. PLOS ONE, 2015, 10, e0129334.　 DOI:10.1371/journal.pone.0129334 June 12, 2015.
   


7. ・ Construction of a chiral quaternary carbon center by a radical cyclization/ring?enlargement reaction: synthesis of 4α-azidoethyl carbocyclic ribose, a key unit for the synthesis of cyclic ADP^ribose derivatives of biological importance. T. Sato, T. Tsuzuki, S. Takano, K. Kato, H. Fukuda, M. Arisawa, S. Shuto. Tetrahedron, 2015, 71, 5403-5413.
   


8. ・ Synthesis of 7-Deaza-Cyclic Adenosine-5’-Diphosphate-Carbocyclic-Ribose and its 7-Bromo Derivative as Intracellular Ca2+-Mobilizing Agents. S. Takano, T. Tsuzuki, T. Murayama, T. Sakurai, H. Fukuda, M. Arisawa, S. Shuto. The Journal of Organic Chemistry, 2015, 80, 6619?6627. DOI: 10.1021/acs.joc.5b00723.
   


9. ・ Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3-Adrenergic Receptor Agonists without Cardiovascular Side Effects. Y. Wada, H. Shirahashi, T. Iwanami, M. Ogawa, S. Nakano, A. Morimoto, K. Kasahara, E. Tanaka, Y. Takada, S. Ohashi, M. Mori, S. Shuto. Journal of Medicinal Chemistry, 2015, 58, 6048-6057. doi: 10.1021/acs.jmedchem.5b00638.
   


10. ・ Safe Removal of the Allyl Protecting Groups of Allyl Esters using a Recyclable, Low-leaching and Ligand-free Palladium Nanoparticle Catalyst. K. Takagi, H. Fukuda, S. Shuto, A. Otaka, M. Arisawa. Advanced Synthesis & Catalysis, 2015, 357, 2129-2124, DOI 10.1002/adsc.201500055.
    


11. ・ One-pot Olefin Isomerization/ Aliphatic Enamine Ring-closing Metathesis/ Oxidation/ 1,3-Dipolar Cycloaddition for the Synthesis of Isoindolo[1,2-a]isoquinolines. Y. Fujii, T. Takehara, T. Suzuki, H. Fujioka, S. Shuto, M. Arisawa, Advanced Synthesis & Catalysis, 2015, 357, 4055-4062.
    

その他の総説等

1. ・ 有澤 光弘 , 西田 篤司 , 周東 智、芳香環エナミドメタセシス反応の開発：生物活性多置換インドール化合物の設計・合成・機能評価、有機合成化学協会誌、2015, 73, 254-266.