【11/5】特別セミナーが開催されました
【11/5】特別セミナーのお知らせ
日時： １１月５日（水曜日）１７時から１時間程度
場所： 理学部５号館３階３０１号室
講演者：
Professor Jenny Martin
ARC Australian Laureate Fellow
Institute for Molecular Bioscience
University of Queensland,
AUSTRALIA
タイトル：
The mystery of membrane fusion: structural biology of Munc18 proteins required for SNARE-mediate vesicle trafficking.
要旨：
Membrane fusion is a fundamentally important process that underpins systems as diverse as neurotransmission and blood glucose control.
The importance of the process is evident by the award of the 2013 Nobel prize in Physiology and Medicine to Rothman, Schekman and Südhof for identifying the molecular components required for fusion and showing that these are conserved from yeast to human. Abnormalities in this process contribute to a wide range of diseases including diabetes and neurological disorders. A key regulator of SNARE-mediated membrane fusion is the Sec1p/Munc18 (SM) protein family. Whilst the molecular basis for SM protein-regulated SNARE complex formation has been extensively studied, it remains poorly understood. The presentation will focus on the structural biology of Munc18 proteins that provide clues to how these enigmatic and highly plastic proteins regulate membrane fusion.
問い合わせは
創薬科学研究教育センターまで
